Results 31 to 40 of about 12,285 (256)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A case study of intra-community conflict as facility impact
Journal of Environmental Planning and Management, 2006 Abstract Through a qualitative case study, this paper describes the everyday experience of conflict as a serious impact of noxious facilities. It describes intra-community conflict over two existing waste facilities (a regional landfill and a low-level hazardous waste facility) in Ryley, Alberta, Canada.
openaire +3 more sources
Exploratory Assessment of Communal Conflict and its Impacts on Nigerian Development
, 2023 communities is an unavoidable component of human existence. It is the result of a variety of circumstances, including environmental, social, political, ethnic, and cultural elements. When it happens, communal conflict is the main reason for starvation, malnourishment, and food insecurity because of the complicated humanitarian crisis that comes with it.
Ilo, Kingsley Obumunaeme +3 more
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HeliyonAcknowledging that violent communal conflicts can lead to increased displacement and overcrowding in IDP camps, this study investigates the impact of such conflicts on internally displaced persons (IDPs) and their camps in Benue State, Nigeria, amid the ...
Christopher M. Anierobi +9 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Frontiers in Psychology, 2022 With the emergence of online open platforms and communities, remix has drawn much attention as an essential source of innovation whereby the knowledge endowment of online community users plays a crucial role. This study constructs a structural equation model to explore the impact of user knowledge endowment heterogeneity on remix through the mediating ...
Juan Tan +4 more
openaire +3 more sources
The Role of Religions in Preventing World Wars [PDF]
Theosophia IslamicaThis text examines the complex and ambivalent role of religion in historical and contemporary global conflicts, particularly focusing on the mechanisms through which religions have influenced the prevention of world wars and promoted peace.
Vedran Obućina
doaj +1 more source