Results 141 to 150 of about 9,839,000 (389)

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Newly estimated disability weights for 196 health states in Hubei Province, China

open access: yesPopulation Health Metrics
Background The disability weight (DW) reflects the severity of non-fatal outcomes and is an important parameter in calculating the burden of disease. However, the universality of the global, national, or subnational DWs remains controversial.
Mengge Zhou   +7 more
doaj   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Communicable Disease Quarterly Report 3rd Qtr 2017 [PDF]

open access: yes, 2017
Communicable disease counts from 1930 to ...

core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Card games are effective tools to enhance foundation year health and safety inductions

open access: yesFEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq   +4 more
wiley   +1 more source

Neck circumference associated with arterial blood pressures and hypertension: A cross-sectional community-based study in northern Han Chinese

open access: yesScientific Reports, 2017
Although several studies have investigated the associations of neck circumference (NC) with arterial blood pressures (BPs) and hypertension, no such studies have been conducted among Northern Chinese population.
Shujun Fan   +7 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

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