Results 171 to 180 of about 9,839,000 (389)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Associations between serum lipid profiles and the incidence of chronic obstructive pulmonary disease in the UK Biobank

open access: yesJournal of Health, Population and Nutrition
Objective To investigate the relationship between serum lipid levels and the risk of Chronic obstructive pulmonary disease (COPD) in the UK Biobank. Methods We performed this prospective study in 381,938 adults without COPD from UK Biobank.
Mengxia Li   +8 more
doaj   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao   +5 more
wiley   +1 more source

Tuberculosis infection control in MDR-TB designated hospitals in Jiangsu Province, China

open access: yesJournal of Clinical Tuberculosis and Other Mycobacterial Diseases
Background: Hospital-acquired Tuberculosis (TB) infections among healthcare workers (HCWs) and patients present a significant challenge due to the increased risk of TB infection within healthcare settings.
Honghuan Song   +9 more
doaj   +1 more source

Gap Analysis of Environmental Health Research in Malawi : Report to the National Commission of Science and Technology [PDF]

open access: yes, 2010
The aim of this consultancy was to assess the current gaps in research for the environmental health sector in Malawi, and to recommend research priorities and an effective action plan to address these ...
Lungu, Kingsley   +2 more
core  

Characteristics of Cerebral Palsy in the Midwestern US

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim   +6 more
wiley   +1 more source

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