Results 71 to 80 of about 9,839,000 (389)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Have purpose‐built vaccine refrigerators reduced the cost of vaccine losses in South Australia?

Australian and New Zealand Journal of Public Health, 2012
Objectives: There is limited epidemiological data on the performance of different refrigerator types for vaccine storage in the real world. This study aims to measure if the introduction of purpose‐built vaccine refrigerators has reduced the cost of ...
Katina D'Onise, Sara Almond, Breda MacDonald, Maureen Watson, Sophie Scrimgeour   +4 more
doaj   +1 more source

The burden of premature mortality in Poland analysed with the use of standard expected years of life lost [PDF]

, 2015
Background: Despite positive changes in the health of the population of Poland, compared to the EU average, the average life expectancy in 2011 was 5 years shorter for males and 2.2 years shorter for females.
Bryła, Marek, Bryła, Paweł, Maniecka-Bryła, Irena, Pikala, Małgorzata   +3 more
core   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Comparison of novel and traditional anthropometric indices in Eastern-China adults: which is the best indicator of the metabolically obese normal weight phenotype?

BMC Public Health
Background People with the metabolically obese normal weight (MONW) phenotype have been confirmed to significantly increase the risk of unfavorable health consequences.
Yijia Chen, Chenchen Wang, Qiannan Sun, Qing Ye, Hairong Zhou, Zhenzhen Qin, Shengxiang Qi, Weiwei Wang, Xin Hong   +8 more
doaj   +1 more source

National mortality burden due to communicable, non-communicable, and other diseases in Ethiopia, 1990–2015: findings from the Global Burden of Disease Study 2015 [PDF]

, 2017
Background: Ethiopia lacks a complete vital registration system that would assist in measuring disease burden and risk factors. We used the Global Burden of Diseases, Injuries, and Risk factors 2015 (GBD 2015) estimates to describe the mortality burden ...
A Misganaw, A Misganaw, Amare Deribew, AR Omran, Awoke Misganaw, Azmeraw T. Amare, B Weldearegawi, Biruck Desalegn Yirsaw, Central Statistical Agency (CSA) [Ethiopia] and ICF, CJL Murray, D Chandramohan, D Hailemariam, D Shamebo, D Shamebo, F Tesfaye, F Tesfaye, Federal Ministry of Health, Ethiopia, GA Biks, GBD 2013 Mortality and Causes of Death Collaborators, Gizachew Assefa Tessema, H Wang, Jed Blore, K Lulu, Kebede Deribe, Kristopher J. Krohn, L Chaker, M Naghavi, Mesoud Mohammed, MH Forouzanfar, Mohsen Naghavi, Molla Gedefaw, Muluken Dessalegn, NJ Kassebaum, P Byass, S Accorsi, S Kuruvilla, Semaw Ferede Abera, Solomon Abrha Damtew, T Araya, Tilahun N. Haregu, Tolesa Bekele, Tom Achoki, W Deressa, Yibeltal Assefa, Yihunie Lakew, Yohannes Adama Melaku   +45 more
core   +2 more sources

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Modeling the burden of long COVID in California with quality adjusted life-years (QALYS)

Scientific Reports
Individuals infected with SARS-CoV-2 may develop post-acute sequelae of COVID-19 (“long COVID”) even after asymptomatic or mild acute illness. Including time varying COVID symptom severity can provide more informative burden estimates for public health ...
Sophie Zhu, Kalyani McCullough, Jake M. Pry, Seema Jain, Lauren A. White, Tomás M. León   +5 more
doaj   +1 more source

Association of poor sleep with multiple chronic conditions among adult residents in Beijing: a cross-sectional survey

Zhongguo gonggong weisheng, 2022
ObjectiveTo analyze the relationship between poor sleep and multiple chronic conditions (MCC) among residents aged 18 – 79 years in Beijing in 2017 for providing reference to the prevention and control of chronic disease comorbidity. MethodsA total of 13
Ying-qi WEI, Ai-juan MA, Jin XIE
doaj   +1 more source

Communicable diseases: provisional summary 2003. [PDF]

, 2004
This report summarises the main trends in communicable disease in Northern Ireland during 2003. It is primarily based on laboratory reports forward to CDSC (NI) and information supplied by Consultants in Communicable Disease Control.

core