Results 141 to 150 of about 2,578,068 (346)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

COVID-19: transferring learning from the pandemic response to non-communicable disease control. [PDF]

Public Health, 2021
Knight J, Day M, Lee ACK, Morling JR.
europepmc   +1 more source

Public health medicine in Malta : past, present and future [PDF]

, 2000
This article highlights some of the significant developments in public health including the pattern of disease in past centuries when emphasis was on sanitation and control of epidemics.
Gilles, Herbert M., Vassallo, A.
core  

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Association and predictive value analysis for mobility assessments and concerns about falling on falls in community-dwelling older adults: a prospective cohort study in China

BMC Geriatrics
Background A series of mobility and concerns about falling measurement instruments are recommended by guidelines for fall prevention in older adults for fall risk assessment.
Jingjing Lin, Lihua Guo, Liuqing You, Na Li, Jieming Zhong, Ming Zhao   +5 more
doaj   +1 more source

Disease Surveillance Networks Initiative Asia: Final Evaluation [PDF]

, 2010
The DSN Initiative was launched in 2007 under the new strategy of the Rockefeller Foundation. The initiative intends:[1] To improve human resources for disease surveillance in developing countries, thus bolstering national capacity to monitor, report ...
Caridad A. Ancheta, Elaine S. Perez, Kerry Richter, Ma. Sandra B. Tempongko, Malee Sunpuwan, Ophelia M. Mendoza, Oranut Pachuen, Pratap Singhasivanon   +7 more
core  

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Lifestyle Profile of Elderly Living with Non-communicable Disease in Bangkok and Surabaya [PDF]

, 2019
Lifestyle is one of the underlying risk factor of non-communicable disease (NCD). Dietary habit and exercise pattern are two indicators of lifestyle. Elderly are prone to NCD due to increased age which being independent risk factor.
Artsanthia, J. (Jintana), Sari, N. P. (Ni)   +1 more
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Improving racial data equity among minority groups in South Carolina using COVID-19 as an example: application of principal components analysis

Population Health Metrics
Background Data inequity occurs when racial and ethnic groups are aggregated during data collection or reporting despite their differences. To demonstrate racial data equity importance, we re-analyzed South Carolina’s (SC) census data and COVID-19 case ...
FNU Rubaiya, Janet O’Connor, Lyubomir N. Kolev, James M. Antill, Margaret Iiams, LaNaya A. Martin, Chantaezia Z. Joseph, Claire Youngblood, Jennifer Almeda-Garrett, Linda E. Kelemen   +9 more
doaj   +1 more source