Results 181 to 190 of about 198,227 (313)

Prevention as a Pillar of Communicable Disease Control: Strategies for Equity, Surveillance, and One Health Integration. [PDF]

Epidemiologia (Basel)
Genovese G, Rizzo CE, Bartucciotto L, Calderone SM, Loddo F, Leonforte F, Mistretta A, Squeri R, Genovese C.   +8 more
europepmc   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Hospital wastewater-based surveillance as an early-warning system for toxigenic <i>Vibrio cholerae</i>: first detection, isolation, characterization, and traceback investigation in Beijing, China. [PDF]

Emerg Microbes Infect
Gao Q, Huang Y, Lv B, Zhang W, Liu B, Gao Z, Qu M, Li S, Hao D, Sun H, Zhou H, Pang B, Tang S, Kan B, Yang P, Wang Q, Zhang D.   +16 more
europepmc   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

From policy to practice: Mapping regional health governance through insights from World Health Organization South-East Asia Regional Committee Meetings (sessions 54-74). [PDF]

J Family Med Prim Care
Kumar P, Wang JDJ, Tjandra S, Abhishek K, Yip YY, Shah BK, Kumar V, Amirah S, Rangan R, Wijaya R, Vaghela G, Xie BX, Respati TAK, Govekar S, Bhasin A, Brar G, Lintang C, Dhaffin, Panchawagh S, Kaushal GP, Agrawal P, Kalra S, Shukla R.   +22 more
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

A "paradox of progress" shapes the social determinants of infectious diseases in Vietnam, 1975-2025. [PDF]

Nat Commun
Quan NK, Taylor-Robinson AW.
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Transition of obesity in India, 2006-2021: a state-wise investigation from an equity perspective. [PDF]

BMJ Glob Health
Rath J, Bera D, Singh L, Ghosal J, Pati S, Dutta A.   +5 more
europepmc   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source