Editorial: Innovative approaches to exercise assessment and prescription in non-communicable diseases. [PDF]
de Abreu RM+3 more
europepmc +1 more source
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
Editorial: Reviews in experimental pharmacology and drug discovery 2023: pharmacological management of non-communicable diseases. [PDF]
Sharif A, Flores-Morales V, Aly HF.
europepmc +1 more source
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo+11 more
wiley +1 more source
Access to medicines and continuity of non-communicable diseases care for forcibly displaced populations: a call for rights-based, comprehensive responses. [PDF]
Aljadeeah S+6 more
europepmc +1 more source
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan+13 more
wiley +1 more source
A chronicle of crises and emergencies: (dis)continuity of care for Syrian refugee children with neglected non-communicable diseases in Lebanon. [PDF]
Gilmour M, Bou-Orm IR.
europepmc +1 more source
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song+6 more
wiley +1 more source
Exploring patients' understanding of behavioral risk factors for non-communicable diseases: a study on diabetes and hypertension in Bushbuckridge, South Africa. [PDF]
Pilusa TD+3 more
europepmc +1 more source