Results 191 to 200 of about 500,263 (272)

Mass Media and Aural Communities

音.樂.學, 2018
openaire   +2 more sources

PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao, Wang Peng, Bin Cheng, Ronghua Wang, Wei Chen, Luyao Liu, Hai Huang, Shiru Chen, Haochen Cui, JingWen Liang, Qiaodan Zhou, Si Xiong, Shuya Bai, Luoxia Liu, Yuchong Zhao   +14 more
wiley   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Wildfire and Smoke Risk Communication: A Systematic Literature Review from a Health Equity Focus. [PDF]

Int J Environ Res Public Health
Sandoval S, Bui J, Hopfer S.
europepmc   +1 more source

Tailoring Piezoelectric Nanogenerators and Microdevices for Cellular Excitation: Impact of Size and Morphology

Advanced Science, EarlyView.
Piezoelectric microdevices, composed of ZnO nanosheets acting as nanogenerators and grown on silicon microparticles, are designed and fabricated to deliver precise electrical cell stimulation. This study optimizes nanosheet growth and microparticle size to enhance electrical cell activation performance while minimizing cellular internalization.
Laura Lefaix, Marc Navarro, Carme Nogués, Andreu Blanquer, Gonzalo Murillo   +4 more
wiley   +1 more source

Menstrual health practices among Tibetan women: An ethnographic participant observation study. [PDF]

J Family Med Prim Care
Dhadwal Y, Kumar A, Pandey SR.
europepmc   +1 more source

An analysis of relationship between interpersonal communication and mass media use by foreign students in the United States

, 1990
Shu-Hua Meng
openalex   +2 more sources

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

Advanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

The direct effects of media exposure on behaviors aimed at preventing COVID-19 and its indirect effects as mediated by interpersonal communication: a longitudinal study in Japan. [PDF]

Front Public Health
Okada H, Okuhara T, Kiuchi T.
europepmc   +1 more source

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source