Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu +21 more
wiley +1 more source
Noncommunicable disease communication campaigns in the Pacific Region: strengths, challenges and lessons learned from an online survey and poster analysis. [PDF]
Strobel F, Protat SB.
europepmc +1 more source
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Media portrayals of alcohol use in pregnancy and fetal alcohol spectrum disorder: A scoping review. [PDF]
Robards FJ, Medlow S, Elliott EJ.
europepmc +1 more source
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source
Culture, context and crisis: understanding community engagement in Ghana's Ashanti and Northern regions amid COVID-19 - a qualitative study. [PDF]
Issahaku GR +4 more
europepmc +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Medical knowledge, political tension, and social relevance: a content and framing analysis of vaccine-related TV broadcasts in the Philippines. [PDF]
Wachinger J +6 more
europepmc +1 more source
New Analytical Models for determining Text Comprehensibility Standards in Mass-Media Communication
Artur Šilić, Slobodan Hadžić
openalex +1 more source

