Results 61 to 70 of about 3,145,370 (305)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

How Swiss is Swiss television? Analysing structural and content references in SRG SSR television programmes

open access: yesStudies in Communication Sciences, 2022
No Billag – in Switzerland, the debate about the necessity and financial viability of public broadcasting has been sparked anew. Closely linked are questions about the public value of the SRG SSR and how much of Switzerland is actually portrayed on Swiss
Eva Spittka   +3 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Information of Personality Disorder as a Negative Impact of Social Media Through Infographic for Teenagers [PDF]

open access: yes, 2019
The development of current technology makes the flow of information is speeding up. Nowadays, people have a dependency on using social media leaning to increase. Most people utilize social media for communication, socialization, or just lifestyle.
Adha, K. K. (Kevyn )   +3 more
core  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Leveraging logit uncertainty for better knowledge distillation

open access: yesScientific Reports
Knowledge distillation improves student model performance. However, using a larger teacher model does not necessarily result in better distillation gains due to significant architecture and output gaps with smaller student networks. To address this issue,
Zhen Guo   +3 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Competing for attention in social communication markets [PDF]

open access: yes, 2016
We investigate the incentives for social communication in the new social media technologies. Three features of online social communication are represented in the model. First, new social media platforms allow for increased connectivity; i.e., they enable
Iyer, G, Katona, Z
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Communication and Cyber Security issues in Smart Grid [PDF]

open access: yes, 2016
Smart Grid is an Information and Communication Technology (ICT) enabled Power grid. It is efficient, secure, reliable and self-healing power grid. Integration of micro grids, electric vehicles and other utilities make it more interesting.
Tripathi, M. M. (M)
core  

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