Results 41 to 50 of about 456,214 (318)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

COM723: Communication research seminar / Faculty of Communication and Media Studies [PDF]

open access: yes, 2018
The aim of this course is to expose students the two major paradigms (types) in research methodology: quantitative and qualitative. Students will also learn how to write research proposal for both types of researches concerning with issues in ...
UiTM, Faculty of Communication and Media Studies
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

COM362: Marketing communication / Faculty of Communication and Media Studies [PDF]

open access: yes, 2018
The Principles of Marketing course is compulsory for all Communication and Media Studies students. This is an introductory course to marketing. Students will study the basic aspects and concepts, major approaches, and theories and practices of marketing.
UiTM, Faculty of Communication and Media Studies
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

“I Don’t Care About Politics, I Just Like That Guy!” Affective Disposition and Political Attributes in Information Processing of Political Talk Shows

open access: yesInternational Journal of Communication, 2017
Drawing on the affect infusion model and on affective disposition theory, this study aims to explain the influence of viewers’ affective disposition toward the guests of political TV talk shows on their information processing and judgments.
Carina Weinmann   +6 more
doaj  

Licensed to Learn: A Case of TV and Radio Channels in Pakistani Universities

open access: yesInternational Journal of Distance Education and E-Learning, 2020
Physical infrastructure for education is harder to lay out in Pakistan but PEMRA is doing well to issue licences to universities to set up TVs and radios to promote education.
Hassan Shehzad   +2 more
doaj   +1 more source

COM710: Communication theories / Faculty of Communication and Media Studies [PDF]

open access: yes, 2018
Expose students on communication, mass communication and media theories in term of the definition of theories, functions, traditions, relation with researcher, ethics, development and ...
UiTM, Faculty of Communication and Media Studies
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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