Results 91 to 100 of about 423,241 (305)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Universality of EPR Pairs in Entanglement-Assisted Communication Complexity, and the Communication Cost of State Conversion [PDF]
, 2019 In this work we consider the role of entanglement assistance in quantum communication protocols, focusing, in particular, on whether the type of shared entangled state can affect the quantum communication complexity of a function.
Harrow, Aram W., Coudron, Matthew
core +1 more source
Pseudodeterministic Communication Complexity
CoRRWe exhibit an $n$-bit partial function with randomized communication complexity $O(\log n)$ but such that any completion of this function into a total one requires randomized communication complexity $n^{Ω(1)}$. In particular, this shows an exponential separation between randomized and \emph{pseudodeterministic} communication protocols.
Mika Göös +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Lower bounds in communication complexity and learning theory via analytic methods
, 2009 textA central goal of theoretical computer science is to characterize the limits of efficient computation in a variety of models. We pursue this research objective in the contexts of communication complexity and computational learning theory.
Sherstov, Alexander Alexandrovich
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
On The Communication Complexity of Property Testing in Graphs
, 2017 I will describe recent work on the multi-party (number-in-hand) communication complexity of property testing in graphs, particularly testing triangle-freeness. I will also discuss open problems in this area arising from distributed computing.
Oshman, Rotem
core
Quantum Communication Complexity with Coherent States and Linear Optics [PDF]
, 2014 We introduce a general mapping for encoding quantum communication protocols involving pure states of multiple qubits, unitary transformations, and projective measurements into another set of protocols that employ coherent states of light in a ...
Lütkenhaus, Norbert +1 more
core +1 more source
Private membership test protocol with low communication complexity
Digital Communications and Networks, 2020 We introduce a practical method to perform private membership tests. In this method, clients are able to test whether an item is in a set controlled by the server without revealing their query item to the server.
Sara Ramezanian +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source