Results 51 to 60 of about 372,914 (263)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Scheduling the Exchange of Context Information for Time-Triggered Adaptive Systems

Algorithms
This paper presents a novel metascheduling algorithm to enhance communication efficiency in off-chip time-triggered multi-processor system-on-chip (MPSoC) platforms, particularly for safety-critical applications in aerospace and automotive domains.
Daniel Onwuchekwa, Omar Hekal, Roman Obermaisser   +2 more
doaj   +1 more source

Efficient extensions of communication values [PDF]

Annals of Operations Research, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sylvain Béal, André Casajus, Frank Huettner   +2 more
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Distributionally Robust Federated Learning With Client Drift Minimization

IEEE Transactions on Machine Learning in Communications and Networking
Federated learning (FL) faces critical challenges, particularly in heterogeneous environments where non-independent and identically distributed (non-IID) data across clients can lead to unfair and inefficient model performance. We introduce DRDM, a novel
Mounssif Krouka, Chaouki Ben Issaid, Mehdi Bennis   +2 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

THE URGENCY OF ASSERTIVENESS IN A GLOBAL WORLD [PDF]

Challenges of the Knowledge Society, 2022
This paper is a plea for learning and practicing assertive behavior in all areas of social life. First of all, it aims to clarify the notion of assertiveness and to delimit the assertive behavior from the aggressive and passive one.
Elena NEDELCU
doaj  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

СРАВНИТЕЛЬНЫЙ АНАЛИЗ РАЗЛИЧНЫХ ТЕХНОЛОГИЙ РАДИОТЕЛЕФОННОЙ СВЯЗИ DECT, GSM, CDMA

Cifra: Информационные технологии и телекоммуникации
В данной статье проведен сравнительный анализ трех основных технологий радиотелефонной связи: DECT, GSM и CDMA. Каждая из этих технологий имеет свои уникальные особенности, области применения и происточные преимущества и недостатки.
Галыгин С.С., Маяков А.К., Сергеев А.Э.   +2 more
doaj   +1 more source