Results 101 to 110 of about 11,339,653 (392)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Infinite Communication Complexity [PDF]

open access: yes, 2014
Suppose that Alice and Bob are given each an infinite string, and they want to decide whether their two strings are in a given relation. How much communication do they need? How can communication be even defined and measured for infinite strings? In this
Guillon, Pierre, Jeandel, Emmanuel
core   +3 more sources

Complexity science and intentional systems

open access: yes, 2008
In their position paper entitled "Towards a new, complexity science of learning and education", Jorg et al. (2007) argue that educational research is in crisis.
Leydesdorff, Loet
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Conceptual Model for Communication [PDF]

open access: yes, 2009
A variety of idealized models of communication systems exist, and all may have something in common. Starting with Shannons communication model and ending with the OSI model, this paper presents progressively more advanced forms of modeling of ...
Alsaqa, Alaa   +2 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Vatican-branded science communication [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
The summer now gone has reported two episodes we would like to bring to the attention of the JCOM readers. Two minor pieces of news, unlikely to be in the limelight over the summer, when the media understandably focus on gossips and crime news.
Nico Pitrelli
doaj  

Reframing social exclusion from science communication: Moving away from 'barriers' towards a more complex perspective [PDF]

open access: yes, 2014
Science communication is an increasingly important field of activity,research and policy. It should not be assumed however, that science communication practices provide equitable and empowering opportunities for everyone.
Dawson, E
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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