Results 51 to 60 of about 3,205,370 (304)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Effects of Several Bile Acids on the Production of Virulence Factors by Pseudomonas aeruginosa

open access: yesLife
The presence of bile acids in the cystic fibrosis patient’s lungs contributes to an increase in the inflammatory response, in the dominance of pathogens, as well as in the decline in lung function, increasing morbidity.
Noureddine Lomri, Christian Hulen
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

A mix-methods concept testing study of short videos for the national anti-cigarette gift giving campaign in China

open access: yesGlobal Transitions
Objective: The study aimed to evaluate the potential effect of creative concepts and scripts of different short videos for the “National Anti-Cigarette Gift Giving Campaign” during the Chinese Lunar New Year. Methods: The concept testing study used a mix-
Jiaruo Sun   +15 more
doaj   +1 more source

Student-centered teacher responses to student behavior in the classroom: A systematic review

open access: yesFrontiers in Education, 2023
IntroductionEffective communication skills are essential for successful behavior management in the classroom. Teachers who can respond proactively and in a student-centered manner can create a positive and productive learning environment.
Jirina Karasova, Jan Nehyba
doaj   +1 more source

Epistemic Vigilance, Cautious Optimism and Sophisticated Understanding [PDF]

open access: yes, 2012
Humans have developed a critical alertness to the believability and reliability of communication: epistemic vigilance (Sperber et al. 2010). It is responsible for trusting interlocutors and believing interpretations.
Padilla Cruz Manuel
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Hunting the Cell Cycle Snark

open access: yesLife
In this very personal hunt for the meaning of the bacterial cell cycle, the snark, I briefly revisit and update some of the mechanisms we and many others have proposed to regulate the bacterial cell cycle.
Vic Norris
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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