The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
I\u27m Not Rockefeller: Implications for Major Foundations Seeking to Engage Ultra- High-Net-Worth Donors [PDF]
· This article describes how a group of 33 ultrahigh- net-worth philanthropists (UHNWPs) approach their giving. · A few key areas dominated their giving priorities: education; health; poverty and social welfare; and children/youth initiatives each were a
Noonan, Kathleen +2 more
core +2 more sources
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Communication, Affect, & Learning in the Classroom [PDF]
The purpose of the handbook was to synthesize the first three decades of research in instructional communication into a single volume that could help both researchers and instructors understand the value of communication in the instructional process ...
Gorham, Joan +2 more
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Bulgarian General Practitioners' Communication Styles about Child Vaccinations, Mainly Focused on Parental Decision Making in the Context of a Mandatory Immunization Schedule. [PDF]
Dimitrova V +11 more
europepmc +1 more source
GROUNDING IN FACE-TO-FACE CONVERSATION: AN ETHNOGRAPHY STUDY [PDF]
Grounding is the process of achieving mutual understanding or belief about what was said between participants in a conversation. Its role is of a paramount important in communication to succeed.
Kamiluddin, Udin
core +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Analysis of communication styles underpinning clinical decision-making in cancer multidisciplinary team meetings. [PDF]
Soukup T +4 more
europepmc +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source

