Results 71 to 80 of about 1,567,630 (309)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Online social support: an exploratory study of breastfeeding women’s use of internet and mobile applications to obtain peer support [PDF]

, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Online social support is reported to be used by a number of people to obtain social interaction and exchange communication as a way to buffer stressful ...
Burman, Ana Beatriz Santana
core  

A generic communication architecture for end to end mobility management in the Internet [PDF]

, 2007
The proliferation of laptops, cellular phones, and other mobile computing platforms connected to the Internet has triggered numerous research works into mobile networking.
Sénac, Patrick, Patrick Senac, Michel Diaz, Lei Zhang, Zhang, Lei, Diaz, Michel   +5 more
core   +1 more source

Mechanical characteristics of porous SUS630 using additive manufacturing

Journal of Advanced Mechanical Design, Systems, and Manufacturing
Porous metal materials are constructed using selective laser melting (SLM). Porous metals exhibit different physical and mechanical properties, depending on the building conditions.
Tetsuya TASHIRO, Tohma KANAO, Yuya NAGATA, Makoto TSUBOTA   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Quality of communication support for people with severe or profound intellectual disability and complex needs

, 2013
This paper describes the differences in communication strategies between good and poor services for people with severe or profound intellectual disability and complex needs. As part of a wider research project into skilled support (Beadle-Brown et al,
Beadle-Brown, Julie, Whelton, Beckie, Richardson, Lisa, Beecham, Jennifer, Bradshaw, Jill, Leigh, Jennifer S, Bäumker, Theresia, Mansell, Jim   +7 more
core  

Bridging the digital divide: exploring the challenges and solutions for digital exclusion in rural South Africa

Discover Global Society
Digital exclusion remains a pervasive challenge in rural South Africa, reinforcing existing socio-economic disparities, with communities such as Mkatazo village in the Eastern Cape experiencing compounded challenges, including inadequate infrastructure ...
Gardner Mwansa, Matipa Ricky Ngandu, Zolisa Mkwambi   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Do Germans support the Euro? CEPS Working Document No. 359, 15 December 2011 [PDF]

, 2011
This paper analyses public support for the euro in Germany. Drawing from the results of regular Eurobarometer surveys, it finds that the ongoing financial and sovereign debt crisis has reduced support for the euro among German citizens, but not ...
Roth, Felix., Gros, Daniel.
core  

Bridging the Communication Gap: Utilizing Large Language Models to Detect Emotional Distress and Depression in Adolescent Communication for Parental Support [PDF]

peer reviewedIn the digital age, the communication gap between parents and adolescents has increased, presenting challenges to understanding the emotional well-being of their children.
Ruvunangiza, Jeremie Biringanine, Valderrama, Carlos Alberto   +1 more
core   +1 more source