Results 31 to 40 of about 1,269,212 (257)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Geographic Variation in Signal Preferences in the Tropical Katydid Neoconocephalus triops

open access: yesBiology
In communication systems, the signal and preference for the signal have to match, limiting phenotypic variation. Yet, communication systems evolve, but the mechanisms of how phenotypic variation can come into existence while not disrupting the match are ...
Oliver M. Beckers, Johannes Schul
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Modern communication system on the example of police activities in Poland

open access: yesNowoczesne Systemy Zarządzania, 2018
The system of correct communication undoubtedly affects the operation of the entire organization. The communication process is exposed to various barriers that can distort the transmitted content.
Angelika Wilk, Anna Woźnialis
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Medico-sociological analysis of consulting work at ophthalmologic regional hospital: communication approach [PDF]

open access: yesСаратовский научно-медицинский журнал, 2012
The purpose of the article is to considerthe consulting work as a process of social communication. The way of such approach allowed to determine objective and function of communication system of ophthalmologic regional hospital, to consider the problems ...
lorina I.G.   +2 more
doaj  

Data Governance and Sovereignty in Urban Data Spaces Based on Standardized ICT Reference Architectures

open access: yesData, 2019
European cities and communities (and beyond) require a structured overview and a set of tools as to achieve a sustainable transformation towards smarter cities/municipalities, thereby leveraging on the enormous potential of the emerging data driven ...
Silke Cuno   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Communication System Using Natural Language for Robotic Laparoscope Guidance

open access: yesCurrent Directions in Biomedical Engineering
To help with the critical nurse staffing shortages in hospitals worldwide, robotic assistants are designed to handle frequently required tasks in the digital operating room (DOR), such as the guidance of the laparoscopic camera.
Pan Yan   +6 more
doaj   +1 more source

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