Results 71 to 80 of about 1,269,212 (257)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

TO THE QUESTION OF LOCAL CAPACITY AS THE BASIC INDICATOR OF THE EFFICIENCY OF THE FUNCTIONING OF THE MILITARY COMMUNICATION SYSTEM

Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2018
In the article on the basis of the conducted analysis the discrepancy between the existing scientific and methodical apparatus for assessing the effectiveness of the functioning of the military communication system, which is oriented on analog data ...
Andrii O. Zinchenko, Oleksandr M. Nesterov, Catherine A. Zinchenko   +2 more
doaj  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

A COMPLEXITY OF GOING IS NEAR EVALUATION OF EFFICIENCY OF FUNCTIONING THE COMMUNICATION NETWORKS ARE ON CORRESPONDING INDEXES OF QUALITY

Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2018
Improving the efficiency of communication systems in the modern conditions of their development is one of the most urgent scientific and practical problems.
Lev N. Sakovich, Vadim P. Romanenko, Sergey E. Gnatyuk, Igor Y. Rozum   +3 more
doaj  

One-way Video Transmission Technology for Urban Rail Transit Based on EndpointDevices

Chengshi guidao jiaotong yanjiu
[Objective] To meet the integrity, confidentiality and availability requirements for inter-network video transmission of different security levels in urban rail transit system, it is necessary to develop a secure and reliable one-way video transmission ...
ZHANG Lidong, XU Ziheng, WANG Kun
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Non-local/Local Community and the Frequency of Migration: a Form of Communication (the case study of sociological researches in the Sakha (Yakutia) Republic)

Oriental Studies, 2018
The article discusses the difference between such notions as non-local / local community (migrant/non-migrant) in terms of N. Luhmann’s communicative systems theory and ‘geophilosophy’ developed by Gilles Deleuze and Félix Guattari. The analysis has been
D. Vinokurova
doaj  

Key Technologies in Intelligent O&M System Construction for Urban Rail Transit Communication

Chengshi guidao jiaotong yanjiu
[Objective] Aiming to design and construct a high-performance, high-reliability intelligent O&M (operation and maintenance) system for urban rail transit communication and to formulate scientific maintenance strategies, it is necessary to transform ...
WANG Xianlei
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Experimental application of gliders communication system in South China Sea

Frontiers in Communications and Networks
Utilizing the motion characteristics of underwater gliders, a water acoustic communication system based on heterogeneous gliders was designed. The system consists of a surface wave glider and an acoustic underwater glider, which are respectively equipped
Shuyang Jia, Shuyang Jia, Shuyang Jia, Baoheng Liu, Baoheng Liu, Sichen Zou, Xiaochuan Zhang, Xiaochuan Zhang, Xiaochuan Zhang   +8 more
doaj   +1 more source