Results 31 to 40 of about 2,291,416 (288)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Investigation of Fan In and Fan Out Technologies for Multi Core Fiber

Guangtongxin yanjiu, 2021
Spatial division multiplexing based on the multi-core fiber has been believed as a promising and effective way to overcome the foreseeable capacity crunch of single mode fiber transmission. Fan-in Fan-out (FIFO) technology for multi-core fiber is the key
Ying QIU, Jin TAO, Zi-chen LIU, Zhi-xue HE   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Reduced Multiplicative (BURA-MR) and Additive (BURA-AR) Best Uniform Rational Approximation Methods and Algorithms for Fractional Elliptic Equations

Fractal and Fractional, 2021
Numerical methods for spectral space-fractional elliptic equations are studied. The boundary value problem is defined in a bounded domain of general geometry, Ω⊂Rd, d∈{1,2,3}. Assuming that the finite difference method (FDM) or the finite element method (
Stanislav Harizanov, Nikola Kosturski, Ivan Lirkov, Svetozar Margenov, Yavor Vutov   +4 more
doaj   +1 more source

Integration, management and communication of heterogeneous design resources with WWW technologies [PDF]

, 2006
Recently, advanced information technologies have opened new pos-sibilities for collaborative designs. In this paper, a Web-based collaborative de-sign environment is proposed, where heterogeneous design applications can be integrated with a common ...
Ji, S, Li, J, Su, D
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Contextualised learning‐free three‐dimensional body pose estimation from two‐dimensional body features in monocular images

IET Computer Vision, 2016
In this study, the authors present a learning‐free method for inferring kinematically plausible three‐dimensional (3D) human body poses contextualised in a predefined 3D world, given a set of 2D body features extracted from monocular images.
Luis Unzueta, Nerea Aranjuelo, Jon Goenetxea, Mikel Rodriguez, Maria Teresa Linaza   +4 more
doaj   +1 more source

A Near Real-Time Method for Forest Change Detection Based on a Structural Time Series Model and the Kalman Filter

Remote Sensing, 2020
The increasing availability of dense time series of earth observation data has incited a growing interest in time series analysis for vegetation monitoring and change detection.
Martin Puhm, Janik Deutscher, Manuela Hirschmugl, Andreas Wimmer, Ursula Schmitt, Mathias Schardt   +5 more
doaj   +1 more source

Cyberbullying [PDF]

, 2017
Innovative communication technologies have changed in our lives crucially. An easy platform for communication between people from different parts of the world has appeared, which is known as the Internet.
Gerasina, A.V., Stetsyuk, Dar’ya, Zuyenok, I. І.   +2 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source