Results 51 to 60 of about 4,140,262 (329)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Temporal and textual analysis of social media on collective discourses during the Zika virus pandemic

BMC Public Health, 2020
Background While existing studies have investigated the role of social media on health-related communication, little is known about the potential differences between different users groups on different social media platforms in responses to a health ...
May Oo Lwin, Jiahui Lu, Anita Sheldenkar, Ysa Marie Cayabyab, Andrew Zi Han Yee, Helen Elizabeth Smith   +5 more
doaj   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Secrecy Rate Maximizing Beamforming Schemes for the DF Relay Wiretap Channels

IEEE Access, 2018
We consider beamforming schemes for the multi-antenna decode-and-forward (DF) relays that maximize the secrecy rate (SR) in the relay wiretap channel. Both full-duplex (FD) and half-duplex (HD) relays are considered, where the FD relay fights the loop ...
Duckdong Hwang, Janghoon Yang, Eunchul Yoon, Hyoung-Kyu Song, Sung Sik Nam   +4 more
doaj   +1 more source

The Mediating Role of New Media Engagement in This Digital Age

Frontiers in Public Health, 2022
New Media Technologies refer to all kinds of web-related technologies like social networking sites, blogs, online social media networking, and other communication technology forms. The primary purpose of this study is to examine the mediating role of new
Zhang Yujie, Megat Al Imran Yasin, Syed Agil Bin Shekh Alsagoff, Ang Lay Hoon   +3 more
doaj   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Selection and adoption of communication technology in a distributed network [PDF]

, 2012
In recent years there has been a lot of effort to foster better communication between the development projects. Without communication in the project network, results of the project will remain in the level of unconnected statements and findings.
Kalalahti, Joanna, Sihvonen, Mika
core   +2 more sources

The Vital Network: An Algorithmic Milieu of Communication and Control

communication +1, 2016
The biological turn in computing has influenced the development of algorithmic control and what I call the vital network: a dynamic, relational, and generative assemblage that is self-organizing in response to the heterogeneity of contemporary network ...
Sandra Robinson
doaj   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source