Results 51 to 60 of about 21,423 (287)

The multilingual CID-5: A new tool to study the perception of communicative interactions in different languages

Frontiers in Psychology, 2015
The investigation of the ability to perceive, recognize and judge upon social intentions, such as communicative intentions, on the basis of body motion is a growing research area. Cross-cultural differences in ability to perceive and interpret biological
Valeria eManera, Francesco eIanì, Jérémy eBourgeois, Maciej eHaman, Łukasz P. Okruszek, Susan M Rivera, Philippe eRobert, Philippe eRobert, Leonhard eSchilbach, Leonhard eSchilbach, Emily eSievers, Karl eVerfaillie, Kai eVogeley, Tabea evon der Lühe, Sam eWillems, Cristina eBecchio, Cristina eBecchio   +16 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Technical metaphor of railroad switch and communicative action

Pensamiento. Revista de Investigación e Información Filosófica, 2016
The operation of a railroad switch serves as a metaphor in Jürgen Habermas’ discussion on preimplantation diagnosis. This article analyses the agreement between such technical metaphor and the notions of continuity and communicative action, while arguing
José Luis Caballero Bono
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

COLLECTIVE WORK IN THE CONSTRUCTION OF THE NURSING COURSES’ POLITICAL PEDAGOGICAL PROJECT [PDF]

Revista Eletrônica de Enfermagem, 2002
: Out of the analyses of data collected from an interinstitutional research, discusses possible ways ofparticipation and suggests strategies to get teachers, students and professionals from the practical field involved inthe construction and/or ...
Maria Elisabeth Cestari, Rosita Saupe
doaj  

“ASSESSMENT IN DIALOGUE” (AID). ASSESSING THE COMMUNICATIVE ACTION

Respectus Philologicus, 2018
“Assessment in Dialogue” (AID) is a model of Joanna Piasta-Siechowicz addressed to the participants of general education: students-teachers-parents. AID reconciles contradictory tendencies of the philosophy and praxis of student assessment: the pursuit ...
Joanna Piasta-Siechowicz
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source