Results 81 to 90 of about 357,377 (303)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

“ASSESSMENT IN DIALOGUE” (AID). ASSESSING THE COMMUNICATIVE ACTION

open access: yesRespectus Philologicus, 2018
“Assessment in Dialogue” (AID) is a model of Joanna Piasta-Siechowicz addressed to the participants of general education: students-teachers-parents. AID reconciles contradictory tendencies of the philosophy and praxis of student assessment: the pursuit ...
Joanna Piasta-Siechowicz
doaj   +1 more source

Communication Networks, Hegemony, and Communicative Action [PDF]

open access: yes
Communicative action now commonly takes place in electronically mediated global networks and the networks are a powerful form of social ordering. This article analyzes the different forms of power that operate in communicative networks and how these ...
James Tully
core  

Being-in-the-world-with: Presence Meets Social And Cognitive Neuroscience [PDF]

open access: yes, 2006
In this chapter we will discuss the concepts of “presence” (Inner Presence) and “social presence” (Co-presence) within a cognitive and ecological perspective.
Riva, Prof. G.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Recent modifications of the functional and communicative characteristics of english modals [PDF]

open access: yes, 2004
The article deals with the present-day trends in changes and modification of the functional and communicative features of the English modals. These changes are manifested mainly in three main directions which are determined by the changes in social ...
Євченко, В. В.
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

ALGHAZALI DAN KESUKSESANNYA DALAM MENYEBARKAN TEOLOGI SUNNI ASY’ARI

open access: yesAl-A'raf: Jurnal Pemikiran Islam dan Filsafat, 2019
This article aims to describe and analyze the success of Alghazali in spreading Sunni Asy’ari theology. Based on library studies, with Jurgen Habermas's communicative action theory approach, the results of the study show that Alghazali's success in ...
Alma'arif
doaj   +1 more source

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