Results 61 to 70 of about 69,626 (352)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The public policies across the history of education of a science teacher: an analysis from the Habermasian thought

open access: yesInvestigações em Ensino de Ciências, 2009
This paper is part of a larger study on the relations between the public policies and the history of education of science teachers. The leading theoretical benchmark used is the Habermas’s Theory of Communicative Action.
Lizete Maria Orquiza de Carvalho   +1 more
doaj  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Communicative rationality in the standardization of legal relevant criminal conduct [PDF]

open access: yes, 2012
/Keywords: Theory of communicative action, ontology of the sentence, systems, subsystems, role, function, crime of breach of duty, compensation, general and special prevention, rule of law, breach of communicative rationality, institutional rivalry and ...
Ochoa, Diego Fernando Victoria
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Tindakan Komunikatif : Sekilas tentang Pemikiran Jgen Habermas

open access: yesAl-Balagh: Jurnal Dakwah dan Komunikasi, 2016
Benefiting from Jgen Habermas, an intellectual figure, the study intends to answer two key questions. How is Jgen Habermas epistemologic construction, and what is communicative actions in Habermas concept?
Anwar Nuris
doaj   +1 more source

Framing the cuts: an analysis of the BBC’s discursive framing of the ConDem cuts agenda [PDF]

open access: yes, 2013
This study analyses the discursive framing of the British government’s economic policies by BBC News Online. Specifically, it focuses on the coverage of the government’s Comprehensive Spending Review in 2010, in which the details of the Chancellor of
Kay, Jilly Boyce, Salter, Lee
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Is it possible more and better democracy? Democracy as political citizen empowerment / ¿Es posible más y mejor democracia? Democracia como empoderamiento político del ciudadano

open access: yesBarataria, 2014
This article states that the original meaning of the concept of democracy has been distorted and we have not been able to apply appropriate institutional designs to develop it.
Ángel Iglesias   +1 more
doaj   +1 more source

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