Results 101 to 110 of about 173,787,670 (260)

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

2004 integrated water quality monitoring and assessment report

open access: yes, 2004
Title from Web page, last updated 21 May 2004 (viewed Dec. 28, 2004).; Harvested from the web on 11/23/05This report indicates the general condition of Ohio's waters and identifies waters that are not meeting water quality goals.This report indicates the
Ohio EPA. Division of Surface Water.
core  

Health and social consequences of water collection among adolescent girls (aged 11–17) in the Yangala rural health zone, Kasai Central Province, Democratic Republic of Congo, 2024

open access: yesJournal of Global Health Economics and Policy
# Background In the Yangala Rural Health Zone of Kasai Central Province, access to safe drinking water remains a major challenge. Adolescent girls aged 11--17 bear a disproportionate share of this burden, often walking long distances daily to fetch ...
Justin Tshimambu   +3 more
doaj   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

open access: yesAdvanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad   +12 more
wiley   +1 more source

Cement Industry Pollution and Its Impact on the Environment and Population Health: A Review

open access: yesToxics
The cement industry, a foundation of global infrastructure development, significantly contributes to environmental pollution. Key sources of pollution include dust emissions; greenhouse gases, particularly carbon dioxide; and the release of toxic ...
Alina Bărbulescu, Kamal Hosen
doaj   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

open access: yesAdvanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo   +20 more
wiley   +1 more source

Other title: Kansas Municipal Water Conservation Plan Guidelines; Other title: Municipal Water Conservation Plan Guidelines

open access: yes, 2007
application/pdf; "August 2007.", "Prepared cooperatively by: Kansas Water Office, Kansas Department of Agriculture, Division of Water Resources, Kansas Department of Health & Environment, Division Of Environment, Bureau of Water, [and] Kansas Rural ...
Kansas Water Office.
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Mitigating sea-level rise in Indonesia: A policy approach through social protection and sustainable water governance

open access: yesSustinere: Journal of Environment and Sustainability
Sea-level rise constitutes a pressing challenge for Indonesia, a nation acutely vulnerable due to its archipelagic geography. This article employs a normative legal research method to critically examine Indonesia’s legal and policy framework for ...
muhamad Pelengkahu
doaj   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

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