Results 21 to 30 of about 5,432,686 (197)

ETIOLOGICAL FEATURES AND ANTIMICROBIAL RESISTANCE IN HEALTHCARE-ASSOCIATED PNEUMONIA

open access: yesArta Medica, 2020
Objectives. Healthcare-associated pneumonia develops in patients undergoing regular medical procedures or has a longterm contact with the hospital environment. Several studies have shown important differences in healthcare-associated pneumonia, comparing
Cristina Toma   +2 more
doaj   +1 more source

The pneumonia severity index predicts time to clinical stability in patients with community-acquired pneumonia

open access: yes, 2006
SETTING: A total of 33 hospitals in 13 countries in North America, Europe, Africa, Asia and Latin America. OBJECTIVE: To investigate the relationship between the pneumonia severity index (PSI) and the time to clinical stability from intravenous to oral ...
A. LaJoie   +16 more
core   +2 more sources

An Approach to Pneumonia in Immunocompetent Patients

open access: yesMcGill Journal of Medicine, 2021
Pneumonia is a leading cause of morbidity. Pneumonia is defined as a lung inflammation of infectious etiology. It can be subcategorized into Community Acquired Pneumonia, Hospital Acquired Pneumonia and Ventilator Acquired Pneumonia.
Spandana Veeravalli, Safiya Soullane
doaj   +1 more source

Possibilities of predicting of the non-severe community-acquired pneumonia outcomes in patients with type 2 diabetes mellitus or chronic heart failure

open access: yesZaporožskij Medicinskij Žurnal, 2014
Aim. Сommunity-acquired pneumonia is life-threatening disease with level of fatal events in hospitals within 12-36 %. In turn, presence of congestive heart failure or type 2 diabetes increases the risk of adverse outcomes in patients with community ...
O. S. Makharynska   +2 more
doaj   +1 more source

Real‐world effectiveness and safety of secukinumab in giant cell arteritis: an Italian multicentre cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in giant cell arteritis (GCA) patients. Methods This multicentre retrospective study included patients with GCA who received secukinumab at 14 Italian centres with at least 6 months of follow‐up.
Luca Iorio   +29 more
wiley   +1 more source

Hospital management of community-acquired pneumonia in Malta [PDF]

open access: yes, 2012
Community-acquired pneumonia (CAP) remains a common diagnosis requiring hospital admission and a leading cause of death worldwide. No local guideline is currently available for the management of CAP.
Mamo, Jonathan   +3 more
core  

A Clinical Comparative Study of Piperacillin and Sulbactam/Ampicillin in Patients with Community-Acquired Bacterial Pneumonia [PDF]

open access: yes, 2009
Objective To evaluate the clinical usefulness of piperacillin (4 g/day) therapy for community-acquired pneumonia compared to sulbactam/ampicillin (6 g/day).
Higashiyama, Yasuhito   +10 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Interrelation between systemic inflammation markers, endothelial dysfunction and coronary heart disease clinical course after community-acquired pneumonia

open access: yesPatologìâ, 2015
Extensive research has established that community acquired pneumonia has negative impact on clinical course on coronary heart disease (CHD), but the pathogenic mechanism was not understood. Aim. To study the pro-inflammatory biomarkers and endothelial
N. S. Mykhailovska , T. O. Kulynych
doaj   +1 more source

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