Results 51 to 60 of about 29,397,977 (254)

Is community-based health insurance an equitable strategy for paying for healthcare? Experiences from southeast Nigeria.

, 2009
OBJECTIVES: To determine how equitable enrolment and utilization of community-based health insurance is in two communities with varying levels of success in implementing the scheme.
Eze, Soludo, Onwujekwe, Obinna, Eze, Soluda, Onoka, Chima, Uzochukwu, Benjamin, Okoli, Chijioke, Obikeze, Eric   +6 more
core   +1 more source

Musculoskeletal pain in adolescents: a systematic review of predictive and associated factors

BMC Pediatrics
Background Musculoskeletal (MSK) pain, especially low back pain (LBP), neck and shoulder pain is common among adolescents and imposes substantial health and economic burdens.
Negar Yazdani, Maryam Shaygan, Sara Shojaei Zarghani, Mehrvash Hemati, Neda Jamlimoghadam   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Integrated Community-Based Care for Dependent Older People Community Participation in Preparation for Recurrent Outbreaks of COVID-19. [PDF]

J Multidiscip Healthc
Supichaya Wangpitipanit,1 Sangduen Piyatrakul,1 Thida Tongvichean2 1Division of Community Health Nursing, Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Faculty of Nursing, Shinawatra ...
Wangpitipanit S, Piyatrakul S, Tongvichean T.   +2 more
europepmc   +2 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Effect of a mobile-based resilience training program on resilience and well-being outcomes in individuals with chronic pain

Scientific Reports
Considering the limited resilience demonstrated by individuals suffering from chronic pain, this study aimed to explore how a mobile app designed to enhance resilience against pain affects the resilience, psychological and social well-being of ...
Hajar Haghshenas, Nilofar Pasyar, Maryam Shaygan, Masoume Rambod   +3 more
doaj   +1 more source

Explosive multi-site metastasis temporally associated with acute exacerbation of idiopathic pulmonary fibrosis in a patient with surgically resected lung squamous cell carcinoma: a case report

Frontiers in Medicine
We report a rare case of a 78-year-old male with lung squamous cell carcinoma (SCC) and concurrent idiopathic pulmonary fibrosis (IPF) who underwent thoracoscopic partial left upper lobectomy and systematic mediastinal lymph node dissection.
Junyi Mu, Junyi Mu, Yi Ding, Yi Ding, Yunxia Yu, Yunxia Yu, Rong Jiang, Rong Jiang, Zhijun Jie, Zhijun Jie, Jingjing Feng, Jingjing Feng   +11 more
doaj   +1 more source