Results 51 to 60 of about 1,431,571 (289)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A systematic review of the international published literature relating to quality of institutional care for people with longer term mental health problems. [PDF]

, 2009
BACKGROUND: A proportion of people with mental health problems require longer term care in a psychiatric or social care institution. However, there are no internationally agreed quality standards for institutional care and no method to assess common care
Brangier, P, Caldas-de-Almeida, J, Cardoso, G, Cervilla, JA, Dimitrov, H, Gonidakis, F, Kalisová, L, Kallert, TW, Kiejna, A, Killaspy, H, King, MB, Mezzina, R, Onchev, G, Piotrowski, P, Ploumpidis, D, Raboch, J, Schuster, M, Taylor, TL, Turton, P, Visser, E, White, S, Wiersma, D, Wolf, K, Wright, C   +23 more
core   +6 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Strengthening Primary Health Care Through Community Health Workers: Investment Case And Financing Recommendations [PDF]

, 2015
A report released this week at the Third International Conference on Financing for Development found that there is a strong case for investing in Community Health Worker (CHW) programs as part of integrated health systems.
Addis Tamire Woldemariam, Akiko Maeda, Bernice Dahn, Chunling Lu, Drew Von Glahn, Henry Perry, Katy Vosburg   +6 more
core  

Integration of substance use disorder services with primary care: health center surveys and qualitative interviews. [PDF]

, 2014
BackgroundEach year, nearly 20 million Americans with alcohol or illicit drug dependence do not receive treatment. The Affordable Care Act and parity laws are expected to result in increased access to treatment through integration of substance use ...
Gelberg, Lillian, Rawson, Richard, Teruya, Cheryl, Urada, Darren   +3 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Formative exploration of students’ perception about Community Medicine teaching at Mahatma Gandhi Institute of Medical Sciences, Sewagram, India [PDF]

, 2008
Objective: The objectives of the present formative research were to explore the medical undergraduates’ study problems and their perceptions about various teaching approaches in currently practiced teaching curriculum of Community Medicine.
Deshmukh, PR, Dongre, AR, Garg, BS
core   +1 more source

Community hospitals and their services in the NHS: identifying transferable learning from international developments - scoping review, systematic review, country reports and case studies [PDF]

, 2017
Background: The notion of a community hospital in England is evolving from the traditional model of a local hospital staffed by general practitioners and nurses and serving mainly rural populations.
Ball, S., Corbett, J., Elmore, N., King, S., Ling, T., Miani, C., Miler, J, Nolte, E., Pitchforth, Emma, van Teijlingen, Edwin, Winpenny, E.M.   +10 more
core   +5 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Facilitators and barriers to teaching undergraduate medical students in general practice [PDF]

, 2019
CONTEXT Globally, primary health care is facing workforce shortages. Longer and higher-quality placements in primary care increase the likelihood of medical students choosing this specialty.
Alberti, Hugh, Barber, John Richard George, Jensen, Kim, Marshall, Hannah, McDonald, Paula, McKinley, Robert Kee, Park, Sophie Elizabeth, Randles, Hannah   +7 more
core   +2 more sources