Results 61 to 70 of about 1,431,571 (289)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Living with young onset dementia: Reflections on recent developments, current discourse, and implications for policy and practice [PDF]

, 2020
© The Author(s) 2020. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which ...
Goodman, Claire, Littlechild, Brian, Mayrhofer, Andrea, Russell, Sarah, Shora , Shaheen, Tibbs, Margaret-Anne   +5 more
core   +2 more sources

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Perceptions of the primary health care team about the implementation of integrated care of patients with type 2 diabetes and hypertension in Slovenia: qualitative study

BMC Health Services Research, 2023
Background Integrated care involves good coordination, networking, and communication within health care services and externally between providers and patients or informal caregivers.
Nataša Stojnić, Zalika Klemenc-Ketiš, Majda Mori Lukančič, Črt Zavrnik, Antonija Poplas Susič   +4 more
doaj   +1 more source

Integrated care in German mental health services as benefit for relatives – a qualitative study [PDF]

, 2016
Background: As mental health services undergo the process of deinstitutionalization, this is resulting in a higher burden of care for relatives. Evidence suggests that interventions for carers have a beneficial impact on their psychological health.
Bramesfeld, Anke, Götz, Katja, Magez, Julia, Ruppert, Daniel, Stegbauer, Constance, Valentini, Jan   +5 more
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

コミュニティにおける生き粋びぜん体操の介護予防効果 [PDF]

, 2018
：[Aims] Based on the Integrated Community Care System, it has produced exercise leader in Bizen City, Okayama prefecture. Community prevention of long-term care prevention is being carried out there.
三浦 隆, 前川 真姫, 古山 喜一, 宮川 健, 早田 剛, 飯出 一秀   +5 more
core   +1 more source

Effectiveness of community-based integrated care in frail COPD patients: a randomised controlled trial [PDF]

, 2016
Background: Chronic obstructive pulmonary disease (COPD) generates a high burden on health care, and hospital admissions represent a substantial proportion of the overall costs of the disease.
Alonso, Albert, García Aymerich, Judith, Gomez, M. del Carmen, Hernández, Carme, Marti, Dolors, Narsavage, Georgia, NEXES consortium, Roca Torrent, Josep, Rodríguez-Roisin, Robert, Serra Renom, Ignacio   +9 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

How well do Health Surveillance Assistants (HSAs) — Malawi’s cadre of community health workers — deliver integrated services? [PDF]

, 2017
HSAs are Malawi’s government-paid cadre of community health workers. Over the past decade, the HSAs’ portfolio of interventions has expanded in number and complexity to include maternal, newborn, and childhealth (MNCH) and family planning (FP).However ...
O'Hare, Bernadette Ann-Marie
core