Results 161 to 170 of about 63,353 (205)

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

open access: yesAdvanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang   +9 more
wiley   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

open access: yesAdvanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu   +8 more
wiley   +1 more source

Community-based participatory research to guide adoption of culturally responsive trauma-informed HIV care throughout Nashville, Tennessee. [PDF]

open access: yesBMC Health Serv Res
Brown LL   +25 more
europepmc   +1 more source

Co-Designing Peer Support Interventions for Adolescents with Type 1 Diabetes and Their Caregivers: A Novel Integration of Community-Based Participatory Research and Human-Centred Design Thinking.

open access: yesHorm Res Paediatr
Abdullah S   +10 more
europepmc   +1 more source

Empowering community partners in health disparities research: Refining a community-based participatory research (CBPR) training curriculum. [PDF]

open access: yesPedagogy Health Promot
Castro-Figueroa E   +11 more
europepmc   +1 more source

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