Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu +19 more
wiley +1 more source
From Participants to Community Partners: A Novel Community-Based Participatory Research (CBPR) Approach to Autistic-Led Inquiry in Digital and Virtual Environments. [PDF]
Grillo VD, Zani M, Veronesi V, Venuti P.
europepmc +1 more source
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Breaking barriers to completing genetic testing for inherited breast cancer among at-risk Black women using a community-based participatory research approach. [PDF]
Choi SH +6 more
europepmc +1 more source
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu +18 more
wiley +1 more source
Empowering promotoras through community-based participatory research in Latinx and Indigenous Mexican communities during the COVID-19 pandemic. [PDF]
Cheney AM +10 more
europepmc +1 more source
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao +12 more
wiley +1 more source
Co-production of informal settlement health: a community based participatory research program for building healthy communities in urban informal settlements of Salvador, Brazil. [PDF]
Mogaji H +26 more
europepmc +1 more source

