A community-based participatory research approach to the development, refinement, and distribution of Test-to-PrEP: a peer-to-peer distributed at-home HIV self-test and prevention information kit in Miami-Dade, Florida. [PDF]
Butts S +8 more
europepmc +1 more source
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He +17 more
wiley +1 more source
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl +27 more
wiley +1 more source
Recovery housing and on-the-ground research priorities: a scoping study through the lens of community based participatory research. [PDF]
Hibbard PF +10 more
europepmc +1 more source
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang +11 more
wiley +1 more source
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi +6 more
wiley +1 more source
Evaluation of a health promotion program based on Community-based Participatory Research for older adults at risk for metabolic syndrome: a mixed methods study. [PDF]
Yang J, Park B.
europepmc +1 more source
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
Reducing syndemics of non-communicable chronic diseases in Mayan Indigenous population through community-based participatory research: a mixed-methods study protocol. [PDF]
Motte-García E +10 more
europepmc +1 more source

