Results 41 to 50 of about 6,866,915 (265)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Transitions at the end of life for older adults - patient, carer and professional perspectives [PDF]
, 2014 BackgroundThe end of life may be a time of high service utilisation for older adults. Transitions between care settings occur frequently, but may produce little improvement in symptom control or quality of life for patients.
Gunn Grande +20 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Older adults, falls and technologies for independent living: a life space approach [PDF]
, 2011 This paper draws attention to the need for further understanding of the fine details of routine and taken-for-granted daily activities and mobility. It argues that such understanding is critical if technologies designed to mitigate the negative impacts ...
FORAN, TIMOTHY G. +9 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Relationship between social frailty and disability risk among community-dwelling older adults [PDF]
Alexandria Scientific Nursing JournalBackground: Social frailty, a multidimensional concept, involves reduced social activitiesand a lack of social support. It is prevalent among older adults and has multiple negativeconsequences, including disability risk.
Sarah Ali Hafez +3 more
doaj +1 more source
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2023 The COVID-19 pandemic increased social isolation for many older adults, causing concern for their health and well-being. To enhance understanding of how community-dwelling older adults were impacted by prolonged social isolation during COVID-19, a ...
A. Garnett PhD +5 more
doaj +1 more source
Sālmand, 2021 Objectives: Social participation in older adults is one of the key pillars of active aging. Social participation is influenced by multiple underlying factors.
Amene Setareh Forouzan +3 more
doaj +1 more source
Experiences of receiving an mHealth application with proactive nursing support among community-dwelling older adults: a mixed-methods study [PDF]
Background As the population ages, a plethora of digital and mobile health applications for assistance with independent living have emerged. Still unknown, however, is how older adults sustain the use of these applications.
Chow, Karen Kit Sum +6 more
core +1 more source
Psychometric properties of the Canadian Occupational Performance Measure in home-dwelling older adults [PDF]
, 2016 Background: The Canadian Occupational Performance Measure (COPM) is an occupational therapy instrument designed to help participants identify, prioritize, and evaluate performance of important occupations.
Tuntland, Hanne Kristin +5 more
core +1 more source