Results 81 to 90 of about 1,296,053 (291)

Dual‐Key Genetic Circuit Enables Stable and Self‐Regulated Engineered Bacteria for the Treatment of Ulcerative Colitis

Advanced Science, EarlyView.
A self‐regulated Escherichia coli Nissle 1917 strain equipped with a dual‐key genetic circuit achieved antibiotic‐free stability and programmable lysis for therapeutic protein delivery. By co‐expressing an IL‐2 mutant and Amuc_1100, the engineered bacteria restored immune balance and epithelial integrity, providing a safe and precise approach for ...
Shuaijie Ding, Biao Yang, Xinyu Li, Yi Wang, Chunyu Huang, Wenfei Dong, Wei Xie   +6 more
wiley   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Challenges and barriers in managing Type 2 diabetes: insights from a qualitative study of patients’ experiences at a university hospital in Qassim, Saudi Arabia

Global Health Action
Background Type 2 diabetes is a global health issue, with unique challenges in Qassim, Saudi Arabia. Patients face barriers such as lifestyle, diet, healthcare access, and psychological impacts.
Andrew Dumale Ngo, Mohammed Bien Kulintang, Talal Ali F. Alharbi, Rasha Mohammed Hussein, Hani Al-Najjar, Fadhel Majed Alharbi, Metab Algeffari, Yara H. Sawan   +7 more
doaj   +1 more source

Model for Successful Collaboration: Working with an American Indian Reservation School

Northwest Journal of Teacher Education, 2007
A formal partnership was established between Idaho State University, College of Education and Fort Hall Elementary School on the Fort Hall Shoshone-Bannock Reservation.
Janice L. Hall, Beverly J. Klug
doaj   +1 more source

JNCHC Front & Back Matter, Vol. 20, No 2, Fall/Winter 2019 [PDF]

, 2019
Cover Masthead Contents Call for Papers, Editorial Policy, & Submission Guidelines Dedication -- Art L.

core   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Nursing education in the digital era: the role of digital competence in enhancing academic motivation and lifelong learning among nursing students

BMC Nursing
Background Digital competence is increasingly crucial for academic success and lifelong learning, especially in health education fields such as nursing.
Shaimaa Mohamed Amin, Shimaa Abd El-fattah Mahgoub, Ahmed Farghaly Tawfik, Dalia E. Khalil, Ahmed Abdelwahab Ibrahim El-Sayed, Mohamed Hussein Ramadan Atta, Ali Albzia, Shadia Ramadan Morsy Mohamed   +7 more
doaj   +1 more source

Keighley College: report from the Inspectorate (FEFC inspection report; 125/95 and 80/99) [PDF]

, 1999
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994-95 and 1998 ...

core  

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

Advanced Science, EarlyView.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans, Ronald G. Jones III, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. McCarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach   +8 more
wiley   +1 more source

Cress, C. M., Stokamer, S. T., Van Cleave, T. J., & Kaufman, J. P. (2022). Faculty Service-learning Guidebook: Enacting Equity-centered Teaching, Partnerships, and Scholarship. Stylus Publishing, LLC

Michigan Journal of Community Service Learning
N ...
Bess German, Gina Tremonti Gembel, Gretchen Sheneman, Jada Phelps, Leanne E. Kent, Michelle Snitgen, Paul Schauert, Roberta Howard Hunter, Stephanie Brewer, Taylor Layne Martin   +9 more
doaj   +2 more sources