A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Minimal Interspecies Interaction Adjustment (MIIA): Inference of Neighbor-Dependent Interactions in Microbial Communities [PDF]
An intriguing aspect in microbial communities is that pairwise interactions can be influenced by neighboring species. This creates context dependencies for microbial interactions that are based on the functional composition of the community.
Bernstein, Hans C. +7 more
core +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Sun exposure drives Antarctic cryptoendolithic community structure and composition [PDF]
The harsh environmental conditions of the ice-free regions of Continental Antarctica are considered one of the closest Martian analogues on Earth. There, rocks play a pivotal role as substratum for life and endolithism represents a primary habitat for ...
Coleine, Claudia +4 more
core
Compositional Verification of Asynchronously Communicating Systems
Within a network of asynchronously communicating systems, the complete network is often not known, or even available at run-time. Consequently, verifying whether the network of communicating systems behaves correctly, i.e., the network does not contain any deadlock or livelock, is impracticable.
openaire +3 more sources
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
The influence of vegetation structure and composition on invasibility by Pinus radiata in the Blue Mountains, NSW [PDF]
The exotic tree species Pinus radiata D. Don (in the family Pinaceae) has successfully spread from commercial plantations into adjacent vegetation in southeastern Australia.
Wardle, Glenda M., Williams, Moira C.
core
A multistate dynamic site occupancy model for spatially aggregated sessile communities
Markov community models have been applied to sessile organisms because such models facilitate estimation of transition probabilities by tracking species occupancy at many fixed observation points over multiple periods of time.
Fukaya, Keiichi +4 more
core +1 more source
Native and invasive inoculation sources modify fungal community assembly and biomass production of a chaparral shrub [PDF]
Feedbacks between plants and surrounding soil microbes can contribute to the establishment and persistence of invasive annual grasses as well as limit the success of restoration efforts.
Allen, Edith B +3 more
core

