Results 31 to 40 of about 1,479,606 (249)

Book Review: Local Government and Metropolitan Regions in Federal Systems

open access: yesCommonwealth Journal of Local Governance, 2010
This is the sixth volume in an impressive series published as A Global Dialogue on Federalism. The series is published on behalf of the Forum of Federations (www.forumfed.org) and the International Association of Centers for Federal Studies (http://iacfs.
Jill Symonds, Brian Walisser
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of a specialist nurse-led structured self-management training for peer supporters with type 2 diabetes mellitus with or without comorbid hypertension in Slovenia

open access: yesBMC Nursing
Background The training of peer supporters is critical because the success of the entire peer support intervention depends on the knowledge and experience that peer supporters can share with other patients. The objective of this study was to evaluate the
Tina Virtič Potočnik   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Serious psychological distress among slum dwellers and unhoused people in Ho Chi Minh City, Vietnam: a pilot study

open access: yesTropical Medicine and Health
Background Mental health is reported to be a significant issue among slum dwellers and unhoused (homeless) individuals worldwide, particularly those facing housing instability.
Hitoshi Murakami   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

HIV Care Seeking Pathways and Barriers to the Continuum of Care Faced by Persons Living With HIV in Rural Nepal: A Qualitative Study

open access: yesHealth Expectations
Background The Human Immunodeficiency Virus (HIV) has a major impact on a person's social and personal lives, affecting both physical and mental health.
Amit Timilsina   +6 more
doaj   +1 more source

Transforming ecological knowledge into collaborative action: Lessons of environmental communication from the Balinese Community [PDF]

open access: yesBIO Web of Conferences
Environmental communication is crucial for raising awareness, instilling a sense of urgency, and encouraging participation in conservation efforts. However, scientists and policymakers often face challenges in conveying complex ecological issues clearly ...
Assegaf Achmad Hamudi   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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