Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu +13 more
wiley +1 more source
Stakeholder-driven assessment of optimal waste-to-energy plant selection in the Tamale metropolitan area using the analytical hierarchy process. [PDF]
Tahiru AW, Cobbina SJ, Asare W.
europepmc +1 more source
Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu +19 more
wiley +1 more source
Radiation-Resistant Microbes: Pioneers for Life Beyond Earth. [PDF]
Coleine C, Cordero RJ.
europepmc +1 more source
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Mapping the intellectual structure of the refrigerated vehicle routing problem: research perspectives and structural knowledge gaps. [PDF]
Aristizábal Torres D +3 more
europepmc +1 more source
A Perspective on Interactive Theorem Provers in Physics
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley +1 more source
Operators' good community engagement practices in energy projects: examples from the UK deep geothermal sector. [PDF]
Ryder S, Rohse M, Abesser C.
europepmc +1 more source
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang +12 more
wiley +1 more source
Powering care at the frontlines: healthcare providers' perspectives on solarised primary health centres in rural Karnataka, India, using the WHO HHFA framework. [PDF]
Tadahal V, Dwivedi R, Athe R.
europepmc +1 more source

