Results 161 to 170 of about 496,693 (303)

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

From Community Engagement to Community Emergence: The Holistic Program Design Approach

, 2017
University-community engagement has the potential to positively transform higher education, but community-engaged institutions must overcome challenges related to defining, planning, and assessing engagement activities.
Brennan, Mark, Olson, Brad
core  

A Non‐Canonical Core Transcriptional Regulatory Circuit Orchestrates Chromatin Reprogramming to Drive Osimertinib Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu, Zhenguo Liu, Lizhen Jiang, Andong Huang, Xinqing Lin, Xinyue Li, Bingyuan Liu, Shiwen Hu, Qiang Pan, Junjun Huang, Liyuan Yin, Liling Jiang, Wei Yi, Wenjun Mao, Yueyuan Zheng, Xianping Shi   +15 more
wiley   +1 more source

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

Community Engagement Newsletter, May 2024

Contents: --- Community Engagement Celebration Day --- McElroy Yough Leadership Fund Fellows --- Veridian Community Engagement Fellows --- Seed Coalition-Engaged Campus Awards --- Cedar Valley Leadership Institute --- Changemakers Retreat --- Page ...
University of Northern Iowa. Office of Community Engagement.
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SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Community Engagement Newsletter, September 2025

Contents: --- Fall Volunteer Fair --- The Cedar Valley Collaboration Forum --- Community Engagement Hours --- Events --- Engagement Opportunity --- National Credentialhttps://scholarworks.uni.edu/com_engagement_news/1035/thumbnail ...
University of Northern Iowa. Office of Community Engagement.
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Participatory research and community engagement in climate and health research. [PDF]

Bull World Health Organ
Palmeiro-Silva Y, Nyamwanza A, Vu AN.
europepmc   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Community Engagement newsletter, Faculty of Veterinary, Spring, October 2016

, 2016
News articles with colour photos about the various community engagement projects of the Faculty of Veterinary Science, University of Pretoria.Veterinary Professional Life Community Engagement Project: Mogale Primary School / Anke Roux, Kelly Christen ...
Haden, Jenna-Lee, Botes, Pieter, Roux, Anke, Cathrall, Garrick, Molefi, Rivashan, Barrett, Siobhan, Chiloane, Khutso, Brits, Adriaan, Taylor, Sarah-Joy, Nkagisang, Molebogeng, Simon, Michaela, Christen, Kelly, Maheso, Hendrick   +12 more
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