Results 51 to 60 of about 6,240,874 (294)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Operational strategies for achieving comprehensive cancer center community outreach and engagement objectives: impact and logic models

open access: yesArchives of Public Health
Background The National Cancer Institute’s (NCI) Cancer Center Support Grants (CCSGs) encourages Cancer Centers to address health disparities and reduce the cancer burden in their Catchment Area (CA) through an organized Community Outreach and Engagement
Folakemi T. Odedina   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Symposium Breakout Sessions: 2014 Community Engagement and Research Symposium [PDF]

open access: yes, 2014
Complete list of Breakout Sessions with descriptions for the 4th annual Community Engagement and Research Symposium, held Friday, November 7, 2014 at the University of Massachusetts Medical School, Worcester ...
Community Engagement and Research Symposium
core   +1 more source

University-Community Engagement Conference – UCEC2017

open access: yes, 2017
University-Community Engagement goes beyond mere outreach, as universities seek mutually beneficial relationships with communities to address community issues and needs with a commitment to sharing and reciprocity which embraces two-way partnerships ...
APUCEN, Asia-Pacific University-Community Engagement Network
core   +1 more source

Communities’ views, attitudes and recommendations on community-based education of undergraduate Health Sciences students in South Africa: A qualitative study

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2013
Background: Medical and Health Sciences students in South Africa undertake community-based education (CBE). Health professionals based at host sites are jointly responsible for training of these students in conjunction with university staff.
Langalibalele H. Mabuza   +10 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

PIDapalooza – the open festival for persistent identifiers

open access: yesInsights: The UKSG Journal, 2017
In 2016 three persistent identifier (PID) organizations – Crossref, DataCite and ORCID – together with California Digital Library organized PIDapalooza, the first open festival for PIDs.
Alice Meadows
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Nature prescribing: emerging insights about reconciliation-based and culturally inclusive approaches from a tricultural community health centre

open access: yesHealth Promotion and Chronic Disease Prevention in Canada
This commentary highlights the importance of social and nature prescribing programs reflecting culturally diverse perspectives and practices. Creating and holding space for Indigenous and other worldviews should be a key priority of nature prescribing, a
Anita Vaillancourt   +3 more
doaj   +1 more source

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