Results 191 to 200 of about 214,869 (267)

Working both-ways: the role of culture and relapse prevention medicines in care for unhealthy alcohol use in Aboriginal and Torres Strait Islander Community Controlled Health Services

Background Globally, unhealthy alcohol use disrupts the wellbeing of communities and is a leading cause of premature death and disability. Primary care services help individuals with the full spectrum of unhealthy alcohol use. Incorporating First Nations approaches alongside standard evidence-based (Western) approaches, may improve intervention ...
openaire   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

The overlooked role of primary care in early childhood trauma: comment on 'Early childhood trauma and its long-term impact on cognitive and emotional development'. [PDF]

Ann Med
Şimşek E, Tulumtaş ÖS.
europepmc   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Preventable mortality in Mexico: bridging gaps in chronic disease and ageing care. [PDF]

BMJ Glob Health
Cabrera-Fuentes HA, Hernández Huerta MT, Gutiérrez-Delgado F, López López VH, Elizarrarás-Rivas J, Najera-Segura NS, Jarquín González EE, Sanchez-Vega JT, Perez-Campos Mayoral E, Nivón-Torres GF, Perez-Campos Mayoral L, Serebruany V, Perez-Campos E, Aquino-Jarquin G.   +13 more
europepmc   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Effectiveness of an Educational Intervention on Awareness of Breast and Cervical Cancers and Human Papillomavirus Vaccine Among Healthcare Professionals in Primary Health Centers of Davanagere District, Karnataka, India. [PDF]

Cureus
N V S, Patil M, Davalagi S, A C B, Krishna NP.   +4 more
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Community Health Workers Intervention in Artificial Intelligence-Integrated Personalized Medicine: A Holistic Approach to Polycystic Ovary Syndrome Management. [PDF]

Int J Prev Med
Aggarwal N, Mukhida S.
europepmc   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source