Results 191 to 200 of about 220,497 (262)

Assessment of community knowledge, attitudes, and practices related to schistosomiasis in a hyper-endemic region of the Democratic Republic of Congo: mixed methods. [PDF]

BMC Public Health
Linsuke S, Mpanya A, Mitashi P, Baloji S, Van Geertruyden JP, Lutumba P.   +5 more
europepmc   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Adoption of the Reference Framework for Preventive Care for Older Adults: a study of primary care physicians. [PDF]

Fam Med Community Health
Zhong CC, Chen M, Yang Z, Li Z, Lo CY, Wong WC, Huang J, Wong MC.   +7 more
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Implementation of stroke prevention: a review of challenges and opportunities in the Americas. [PDF]

Lancet Reg Health Am
Martins SO, Ordunez P, Borelli WV, Ovbiagele B, Urrutia VC, Abanto C, Alet MJ, Almarie B, Alvarez TF, Amaya P, Ameriso S, Arauz A, Barboza MA, Bayona H, Calleja J, Cano-Nigenda V, Carbonera LA, Carrillo-Larco RM, Constanzo F, Corredor A, de Souza AC, Diestro JD, Fregni F, Guerrero R, Jimenez C, Lanas F, Martinez R, Moro C, Muñoz-Venturelli P, Navia V, Novarro-Escudero N, Olavarría VV, Bernabé-Ortiz A, Pontes-Neto O, Pujol V, Rabinstein AA, Rosales J, Rosende A, Silva GS, Saposnik G, Sen S, Sposato L, Testai FD, Anderson CS, Lavados PM.   +44 more
europepmc   +1 more source

Graphene (0002)/Diamond (111) Heterojunction with High Piezoresistive Response

Advanced Science, EarlyView.
Graphene/diamond heterostructures show promise as silicon alternatives for semiconductors, but high‐quality integration is challenging. Thermal electron irradiation enables covalent bonding; lonsdaleite acts as an intermediate. The heterostructure exhibits a high piezoresistive response (gauge factor −1149) associated with electron‐rich layers and ...
Xueyu Zhang, Kun Guo, Zhigang Gai, Tianxiao Guo, Yuan Gao, Jiancai Leng, Mei Zhang, Tonggang Jiu, Yibao Wang, Shousheng Liu, Xin Jiang   +10 more
wiley   +1 more source

Women's perceptions of a tailored diabetes education program in underserved Saudi communities: An exploratory sequential mixed-methods study. [PDF]

Medicine (Baltimore)
Alshehri A, Abduljawad AA.
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source