Advanced Science, EarlyView.We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
The added value and unintended negative consequences of public involvement processes in the planning, development and implementation of community health services: Results from a thematic synthesis. [PDF]
Int J Health Plann Manage, 2022 Pedersen JF +3 more
europepmc +1 more source
Healthy Futures—Aboriginal Community Controlled Health Services: report card [PDF]
During 2012-13, Aboriginal Community Controlled Health Services saw just over 250,000 Indigenous clients. This report shows increases in the proportion of clients receiving appropriate processes of care for ten of the 16 primary health care indicators ...
Australian Institute of Health and Welfare
core
Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis
Advanced Science, EarlyView.This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen +7 more
wiley +1 more source
Work competence of general practitioners working in the community health services of Shanghai: a cross-sectional study based on self-assessment. [PDF]
BMC Med Educ, 2022 Wang T +7 more
europepmc +1 more source
Wharekauri, Rēkohu, Chatham Islands health and social needs [PDF]
This report is an independent review of the health and social needs of Chatham Islanders. Executive summary Background: Whānau Ora is about the transformation of whānau/family – with whānau/family setting their direction.
Liz Smith +2 more
core
Advanced Science, EarlyView.Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu +6 more
wiley +1 more source
World Health Organization building blocks in rural community health services: An integrative review. [PDF]
Health Sci Rep, 2021 Stockton DA +3 more
europepmc +1 more source
Advanced Science, EarlyView.This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu +12 more
wiley +1 more source
Access to Home and Community Health Services for Older Adults With Serious, Life-Limiting Illness: A Study Protocol. [PDF]
Am J Hosp Palliat Care, 2021 Hill JD, Cuthel AM, Grudzen CR.
europepmc +1 more source