Results 61 to 70 of about 8,123,307 (251)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ray City Community News. Vol. 3, No. 2, April - June, 1992

open access: yes, 1992
Ray City Community News. Vol. 3, no. 2 (April - June 1992). 1 electronic record (PDF), 1.80 MB (1,888,729 bytes).Ray City Community News. Vol. 3, no. 2 (April - June 1992). Ray City Community Development Council.
Ray City Community Library
core   +1 more source

Pemetaan Potensi Pariwisata Berbasis Komunitas Melalui Eksplorasi Keunikan Seribu Pantai di Malang Selatan

open access: yesEngagement: Jurnal Pengabdian Kepada Masyarakat, 2020
Identifying tourist attractions in each local area needed to exploring the uniqueness of potential to each tourist attraction, and the identification result used for both visitors and residents.
M. R. Khairul Muluk   +2 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Community cohesion: constructing boundaries between or within communities-of-place? [PDF]

open access: yes
This paper is concerned with how communities are constructed symbolically and the relation between such symbolically constructed communities and communities-ofplace.
Vergunst, Petra
core  

Choosing to belong : the influence of choice on social identification and psychological sense of community [PDF]

open access: yes, 2007
The influence of choice on individuals’ social identification and Psychological Sense of Community (PSOC) with their group memberships is a little examined area.
Obst, Patricia L., White, Katherine M.
core   +1 more source

Geographical and temporal distribution of Megalopygidae in the United States and Puerto Rico

open access: yesToxicon: X
Background: The venom of Megalopygidae caterpillars causes inflammation and pain. Understanding geographic and temporal variation in exposure will help physicians and the public understand when and where the species in this family may be encountered ...
Emilio Peruzzi Sancio   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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