Results 61 to 70 of about 1,538,255 (308)

The role of community conversations in facilitating local HIV competence: case study from rural Zimbabwe [PDF]

, 2013
Background This paper examines the potential for community conversations to strengthen positive responses to HIV in resource-poor environments. Community conversations are an intervention method through which local people work with a facilitator to ...
Campbell, Catherine, Gregson, Simon, Madanhire, Claudius, Nhamo, Mercy, Nyamukapa, Constance, Scott, Kerry, Skovdal, Morten   +6 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Creative Placemaking: Building Partnerships to Create Change [PDF]

, 2019
Arts, artists, and creative strategies can be critical vehicles for planning to achieve social, economic, and community goals. Creative placemaking is one type of arts-led planning that incorporates both stakeholder participation and community goals. Yet,
Kim, Mirae, Levine Daniel, Jamie
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Community-based implementation strategy use and satisfaction: A mixed-methods approach to using the ERIC compilation for organizations serving children on the autism spectrum

Implementation Research and Practice, 2021
Background Despite efforts to use standardized taxonomy and research reporting, documenting implementation strategies utilized in community settings remains challenging.
Tatiana Elisa Bustos, Aksheya Sridhar, Amy Drahota   +2 more
doaj   +1 more source

Use of a Systematic Consultation Process to Facilitate Nursing Research Projects: An Exemplar [PDF]

, 2018
PURPOSE/OBJECTIVES: The purpose of this article is to describe the use of a well-established, 5-stage consultation process, to advise a research team on planning strategies to engage domestic violence shelters (DVSs) as community partners in their ...
Draucker, Claire, Martsolf, Donna S., Smith, Carolyn, Tehan, Rebecca   +3 more
core   +1 more source

Elder abuse by abandonment in India: a novel community awareness and intervention strategy [PDF]

International Psychogeriatrics, 2017
India, along with the rest of the world, is aging rapidly, but more so. Of a total population of over 1.2 billion, the aging population over 60 years is 109 million, projected to rise above 300 million by the year 2050, exceeding the younger population. One important ramification of this highly populous and under-resourced setting is that it provides a
Mangal S, Kardile, Carmelle, Peisah
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evaluating community engagement strategies in COVID-19: insights from a National Quasi-Experimental Intervention

BMC Public Health
Background Community engagement is essential during crises such as the COVID-19 pandemic. However, the effectiveness of community engagement during this pandemic, especially in low- and middle-income countries, has not been seriously investigated ...
Hamid Soori, Martha Orendu Oche Attah
doaj   +1 more source

Formative research to develop a school-based, community-linked physical activity role model programme for girls: CHoosing Active Role Models to INspire Girls (CHARMING)

BMC Public Health, 2019
Background Physical inactivity is a persistent challenge among girls. School-based physical activity (PA) interventions have shown mixed effects on girl’s activity levels, with multi-component approaches involving both school and community links ...
Kelly Morgan, Jordan Van Godwin, Kirsty Darwent, Alison Fildes   +3 more
doaj   +1 more source