Results 31 to 40 of about 815,233 (263)

Competence Needs of Modern Virtual Community Members

International Journal of Management, Knowledge and Learning, 2023
Purpose: This paper examines necessary competencies in virtual communities in Higher Education. Therefore, we explore which competencies are needed to participate in a virtual community and how these competencies can be captured and developed ...
Lisa-Marie Langesee, Tom Helleken, Nils Hobe   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Host Country Views of Short‑Term Medical Missions: Community‑Based Research in Ghana, Uganda, and Guatemala

Annals of Global Health
Background: Growing attention to the proliferation of short‑term medical missions (STMMs) in the Global South has increasingly taken the form of critiques of inadequately prepared volunteers, lack of community control and continuity.
Efua Esaaba Mantey, Emilly Maractho, Erwin Calgua‑Guerra, Daniel Doh, Guillermo Zea‑Flores, Carolina López, Sirry Alang, Peter Donkor, Judith N. Lasker   +8 more
doaj   +1 more source

166 Community Driven Research Day: Addressing Community Needs in Rural Pennsylvania

Journal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Describe the community of Norther Dauphin County, PA and increase awareness of this community’s health related needs. Establish partnerships between Penn State faculty and Northern Dauphin County community-based organizations to develop
Andrea E. Murray, Miriam Miller, Aleksandra E. Zgierska   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Jobs-to-Be-Done and Journalism Innovation: Making News More Responsive to Community Needs

Media and Communication
Developing successful innovations in journalism, whether to improve the quality and reach of news or to strengthen business models, remains an elusive problem.
Seth C. Lewis, Alfred Hermida, Samantha Lorenzo   +2 more
doaj   +1 more source

Demographic and dental profile of patients met in the Dental Center for Patients with Special Needs of the Brazilian Association of Dentistry – Rio de Janeiro

Revista Brasileira de Odontologia, 2018
Objective: to evaluate the demographic and dental profile of patients with special needs met in a Reference Center in the state of Rio de Janeiro, showing their main needs and the possibility of outpatient care. Material and Methods: the sample consisted
Bruna Lavinas Sayed Picciani, Bruna Michalski dos Santos, Geraldo Oliveira Silva-Júnior, Thays Teixeira de Souza, Marcelo Brito Faria, Luciana Freitas Bastos   +5 more
doaj   +1 more source