Results 111 to 120 of about 117,157 (312)

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Continuity of medication information transfer and continuous medication supply during hospital-to-home transitions - nationwide surveys in hospital and community pharmacies after implementing new legal requirements in Germany

BMC Health Services Research
Background While successful information transfer and seamless medication supply are fundamental to medication safety during hospital-to-home transitions, disruptions are frequently reported.
Sophia Klasing, Frank Dörje, Heike Hilgarth, Nadine Metzger, Ina Richling, Hanna M. Seidling   +5 more
doaj   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Addressing Resource Gaps in the U.S. Health Care Safety Net: An Assessment of the Free Clinic Network [PDF]

, 2011
Based on a survey of free clinics serving uninsured low-income patients, examines the resource constraints limiting the expansion of healthcare services provided, including the high costs of labs, equipment, and medication.
Tammy J. Allen
core  

Pharmacy Staff Perspectives on Alcohol and Medication Interaction Prevention Among Older Rural Adults [PDF]

, 2018
Older adults are at high risk for alcohol and medication interactions (AMI). Pharmacies have the potential to act as ideal locations for AMI education, as pharmacy staff play an important role in the community.
Allen, Hannah, Antimisiaris, Demetra, Clayton, Richard, Martin, Catherine, Schoenberg, Nancy, Smith, Rachel Vickers, Zanjani, Faika   +6 more
core   +3 more sources

Geographical Disparities in the Distribution of Community Pharmacies Providing Aseptic Preparation Services in Japan

Integrated Pharmacy Research and Practice
Kazuya Nonomura,1,2 Kazuya Toyama,1 Yufu Kondo,1 Hirofumi Tamaki,1 Arihiro Osanai,1 Yoko Ino,3 Mitsuhiro Nakamura,4 Kazuhiro Iguchi1 1Laboratory of Community Pharmacy, Gifu Pharmaceutical University, Gifu, Japan; 2Mamiya Dispensing Pharmacy, Gifu, Japan;
Nonomura K, Toyama K, Kondo Y, Tamaki H, Osanai A, Ino Y, Nakamura M, Iguchi K   +7 more
doaj  

2009 Alaska Health Workforce Vacancy Study [PDF]

, 2009
Alaska continues to experience health professional shortages. The state has long had a deficient “supply side” characterized by insufficient numbers of key health workers whose recruitment, retention, and training have been impeded by Alaska’s ...
DeRoche, Patricia, Doucette, Sanna, Frazier, Rosyland, Hill, Alexandra, Johnson, Kristin, Landon, Beth, Martin, Stephanie, Prator, Donna, Sanders, Kate, Sharp, Suzanne, Silver, Darla, Wilson, Meghan   +11 more
core  

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

The Community Safety Net and Prescription Drug Access for Low-Income, Uninsured People [PDF]

, 2006
Examines strategies adopted by hospitals and community health centers to maintain access to affordable brand name and generic prescription drugs.
Anneliese M. Gerland, Erin Fries Taylor, Laurie E. Felland   +2 more
core  

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source