Results 81 to 90 of about 127,803 (309)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Public’s attitudes towards community pharmacy in Qatar: a pilot study
Patient Preference and Adherence, 2011 Maguy Saffouh El Hajj, Samah Salem, Hend MansoorCollege of Pharmacy, Qatar University, Doha, QatarObjectives: To assess the public’s attitudes towards the community pharmacist’s role in Qatar, to investigate the public’s use
El Hajj MS, Salem S, Mansoor H
doaj
ROLE OF COMMUNITY PHARMACIST IN PHARMACOVIGILENCE
Khyber Medical University Journal, 2019 World Health Organization (WHO) defines pharmacovigilance as the detection, assessment, understanding and prevention of adverse drug reactions or any other possible drug related problems.1 Pharamcovigilance is important for the safe and efficient usage ...
Nayab Farooq, Fatima Amin
doaj +1 more source
New Ways of Working – Pharmacy and Medicines Management [PDF]
, 2012 Medicines play a key role in the treatment of most mental illnesses. The management of those medicines is of great importance to most mental health service users and also impacts on the daily professional life of many of those involved in caring, be they
Branford, David
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Integrating community pharmacy and NHS Direct - pharmacists' views [PDF]
, 2002 AIM:To establish the views of community pharmacists on NHS Direct and its forthcoming integration with community pharmacy. DESIGN: Postal questionnaire survey. SUBJECTS AND SETTING: Pharmacists working in community pharmacies within the area of the
Knowles, E. +3 more
core
Applying Quality Improvement methods to address gaps in medicines reconciliation at transfers of care from an acute UK hospital [PDF]
, 2016 © Published by the BMJ Publishing Group Limited.Objectives Reliable reconciliation of medicines at admission and discharge from hospital is key to reducing unintentional prescribing discrepancies at transitions of healthcare.
Bell, D +5 more
core +1 more source
PharmacyWith the recent shift in community pharmacist services toward in-person services and the growing need for centralized and continuous medication management/monitoring, pharmacist–patient information sharing is crucial.
Ryota Kumaki +6 more
doaj +1 more source