Results 111 to 120 of about 143,471 (289)

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

open access: yesAdvanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong   +27 more
wiley   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Community pharmacy supply of emergency contraception [PDF]

open access: green, 2001
Paul Bissell   +5 more
openalex   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

open access: yesAdvanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang   +10 more
wiley   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li   +16 more
wiley   +1 more source

Extending the Range of Sizes of Monodisperse Core‐Shell Hydrogel Capsules from Composite Jet Breakup by Combined Electrical and Mechanical Actuation

open access: yesAdvanced Science, EarlyView.
We present a microfluidic approach combining electrical and mechanical actuation to improve control over liquid jet breakup and droplet formation. By adjusting excitation frequency and applying an electric field, coalescence is reduced and droplet uniformity is enhanced.
Lucas Suire   +3 more
wiley   +1 more source

Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?

open access: yesAdvanced Science, EarlyView.
Despite advancements in implantable electrode technology, challenges persist in scaling up these devices to record most of the neuronal activity across the cortex. This review explores the limitations of both rigid and flexible probes, including tissue damage and foreign body response, while also discussing emerging biohybrid strategies.
Attila Kaszás   +5 more
wiley   +1 more source

Nature, frequency and determinants of prescription modifications in Dutch community pharmacies [PDF]

open access: green, 2001
Henk Buurma   +3 more
openalex   +1 more source

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