Results 111 to 120 of about 466,680 (301)

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Towards a Greater Professional Standing: Evolution of Pharmacy Practice and Education, 1920–2020

Pharmacy, 2019
The history of community pharmacy in America since the 1920s is one of slow progress towards greater professional standing through changes in pharmacy education and practice.
Benjamin Y. Urick, Emily V. Meggs
doaj   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Helping Patients Access Medications through a Partnership of Caring and Education [PDF]

, 2018
According to the Ohio Poverty Report – 2017, approximately 35 percent of people in Franklin County live at or below 200 percent of the federal poverty level.
Casper, Kristin, Seifert, Jennifer
core  

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

ARIA pharmacy 2018 "Allergic rhinitis care pathways for community pharmacy" [PDF]

, 2018
Pharmacists are trusted health professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact of allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important.
Bosnic-Anticevich, Sinthia, Costa, Elísio, Menditto, Enrica, Lourenço, Olga, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Buonaiuto, Roland, Chrystyn, Henry, Cvetkovski, Biljana, Di Capua, Stefania, Park, Hae-Sim, Phillips, Jim, Plavec, Davor, Stellato, Cristiana, Somekh, David, Sisul, Juan, To, Teresa, Todo-Bom, Ana, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Valero, Antonio, Popov, Todor A, Potter, Paul C, Prokopakis, Emmanuel P, Roller-Wirnsberger, Regina E, Rottem, Menachem, Ryan, Dermot, Samolinski, Boleslaw, Sanchez-Borges, Mario, Schunemann, Holger J, Sheikh, Aziz, Ventura, Maria Teresa, Valovirta, Erkka, Valiulis, Arunas, Wagenmann, Martin, Kritikos, Vicky, Bousquet, Jean, Zuberbier, Torsten, Mair, Alpana, Orlando, Valentina, Paulino, Ema, Salimäki, Johanna, Söderlund, Rojin, Wallace, Dana, Waserman, Susan, Wickman, Magnus, Yiallouros, Panayiotis, Yorgancioglu, Arzu, Yusuf, Osman, Zar, Heather J, Zernotti, Mario E, Zhang, Luo, Zidarn, Mihaela, Wroczynski, Piotr, Williams, Dennis M, Tan, Rachel, Agache, Ioana, Ansotegui, Ignacio J, Cruz, Alvaro A, Sousa, Jaime Correia de, Chavannes, Niels H, Czarlewski, Wienczyslawa, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Philippe, Anto, Josep M, Bedbrook, Anna, Bachert, Claus, Bewick, Mike, Bindslev-Jensen, Carsten, Brozek, Jan L, Canonica, Giorgio Walter, Cardona, Victoria, Carr, Warner, Casale, Thomas, El-Gamal, Yehia, Gaga, Mina, Dykewicz, Mark S, Fonseca, João, Fokkens, Wytske J, Kuna, Piotr, Kowalski, Marek, Klimek, Ludger, Kvedarienė, Violeta, Linnemann, Désirée Larenas, Laune, Daniel, Le Thi Tuyet, Lan, Guzman, Maria Antonieta, Haahtela, Tari, Hellings, Peter, Illario, Maddalena, Ivancevich, Juan Carlos, Just, Jocelyne, Kaidashev, Igor, Khaitov, Musa, Khaltaev, Nikolai, Keil, Thomas, Maier, Dieter, Mahboub, Bassam, Lodrup Carlsen, Karin C, Malva, João, Manning, Patrick J, Okamoto, Yoshitaka, Ohta, Ken, O'Hehir, Robyn, Onorato, Gabrielle L, Palkonen, Susanna, Panzner, Petr, Papadopoulos, Nikolaos G., Almeida, Mário Morais, Mösges, Ralph, Mullol, Joaquim, Münter, Lars, Murray, Ruth, Naclerio, Robert, Namazova-Baranova, Leyla, Nekam, Kristof, Nyembue, Tshipukane Dieudonné, Okubo, Kimihiro, Pfaar, Oliver, Pawankar, Ruby   +121 more
openaire   +5 more sources

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Community pharmacists' interest in and attitude to pharmacy practice research in Ethiopia: A cross-sectional study.

PLoS ONE, 2017
Pharmacy practice-research became an important component in the pharmacy practice. However, limited studies were conducted in sub-Saharan Africa to understand the pharmacists' interest and attitude towards pharmacy practice-research.
Akshaya Srikanth Bhagavathula, Eyob Alemayehu Gebreyohannes, Begashaw Melaku Gebresillassie, Daniel Asfaw Erku, Chernet Tafere Negesse, Yared Belete Belay   +5 more
doaj   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source