Results 161 to 170 of about 4,590,837 (353)
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han +6 more
wiley +1 more source
BackgroundThe intention to more effectively mobilise and integrate the capabilities of the community pharmacy workforce within primary care is clearly stated within National Health Service (NHS) England policy.
Jayne L Astbury +9 more
doaj +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab +16 more
wiley +1 more source
Implementation study of professional pharmacy services in community pharmacies
Introduction: In recent year, the role of the pharmacist has evolved from product-focused to patient-focused activities. Following this evolution, new professional pharmacy services were simultaneously developed by researchers and started to be legally implemented and remunerated for community pharmacists around the world.
openaire +3 more sources
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
Interdisciplinary Medication Adherence Program: The Example of a University Community Pharmacy in Switzerland [PDF]
Mélanie Lelubre +9 more
openalex +1 more source
Making community pharmacies psychologically informed environments (PIE): a feasibility study to improve engagement with people using drug services in Scotland [PDF]
Catriona Matheson +6 more
openalex +1 more source
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao +13 more
wiley +1 more source

