Results 301 to 310 of about 4,721,869 (378)

Exonic Variation and Its Clinical Impact in 7221 Old Order Amish

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Amish of Lancaster County, PA has been the focus of genetic studies for many years due to its demographic history and unique genetic makeup that includes a historical bottleneck event and subsequent genetic drift, resulting in a marked decrease in genetic diversity and increased frequency of some variants that have substantially shaped the
Braxton D. Mitchell   +21 more
wiley   +1 more source

Engaging community pharmacy in tuberculosis case detection (ENHANCE): a study protocol for an implementation study in Indonesia. [PDF]

open access: yesArch Public Health
Pradipta IS   +9 more
europepmc   +1 more source

The Role of SLC39A8.p.(Ala391Thr) in Schizophrenia Symptom Severity and Cognitive Ability: Cross‐Sectional Studies of Schizophrenia and the General UK Population

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The missense SNP NC_000004.12:g.102267552C>T (also known as SLC39A8.p.(Ala391Thr), rs13107325) in SLC39A8 encodes a zinc transporter. This SNP has been linked to schizophrenia and is the likely causal variant for one of the genome‐wide association loci associated with the disorder. Using regression analyses, we tested whether the schizophrenia‐
Sophie E. Smart   +12 more
wiley   +1 more source

Regioselective C─H Functionalization by the Combination of Enzymatic and Chemocatalytic Reactions in Water

open access: yesAngewandte Chemie, EarlyView.
H3CP contributes to sustainable synthesis by integrating regioselective enzymatic halogenation, Pd‐catalyzed Heck coupling, and enzymatic hydrolysis. TPGS‐705‐M micelles enable the Pd‐catalyzed step, allowing seamless compatibility with enzymatic reactions in one vessel under aqueous conditions.
Ran Zhu   +3 more
wiley   +2 more sources

Multi-stakeholder perspective on community pharmacy services in Saudi Arabia: A systematic review and meta-analyses for 2010-2020. [PDF]

open access: yesExplor Res Clin Soc Pharm
Alghamdi KS   +5 more
europepmc   +1 more source

Randomized, Double‐Blind, Placebo‐Controlled, Multiple‐Dose Studies to Assess the Safety and Efficacy of Elezanumab when Added to Standard of Care in Relapsing and Progressive Forms of Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Elezanumab is a monoclonal antibody that binds repulsive guidance molecule a (RGMa), an inhibitor of central nervous system regeneration after inflammation or injury. The aim was to assess the safety and efficacy of elezanumab in relapsing and progressive forms of multiple sclerosis (MS).
Bruce A.C. Cree   +6 more
wiley   +1 more source

Iron‐Catalyzed Carbonylation Reactions with Carbon Monoxide

open access: yesAngewandte Chemie, EarlyView.
Recent developments in iron‐catalyzed carbonylative transformations using CO as a C₁ feedstock are summarized in this minireview. Reaction mechanisms of selected reactions and the potential for further advancements in this field are also discussed. Abstract The utilization of carbon monoxide (CO) as an inexpensive and indispensable C1 feedstock for the
Kangkang Sun   +3 more
wiley   +2 more sources

Using simulated patient methodology to assess sick day guidance in community pharmacy: The case of an elderly patient with diabetes. [PDF]

open access: yesExplor Res Clin Soc Pharm
Coppes T   +5 more
europepmc   +1 more source

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